Platelet rich plasma for photodamaged skin: A pilot study

Lee, Z‐Hye; Sinno, Sammy; Poudrier, Grace; Motosko, Catherine C.; Chiodo, Michael V.; Saia, Whitney; Gothard, David; Thomson, Jennifer E.; Hazen, Alexes

doi:10.1111/jocd.12676

Cited by 37 publications

(29 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…To the best of our knowledge, only two studies have used the FACE-Q to evaluate patient-reported outcomes following use of PRP or PRF monotherapy for facial rejuvenation. 43,44 In one study, Lee and colleagues showed improvement in participant satisfaction with overall facial appearance and cheeks following a single injection of PRF 43 while in the other study Nacopoulos and colleagues that reported an improvement in the satisfaction with skin questionnaire following several sessions of injectable PRF treatment. 44 To our knowledge, the clinical use of injectable PRF for facial aesthetics has only been previously reported in a single study.…”

Section: Discussionmentioning

confidence: 99%

“…In view of the low baseline score for skin adverse effects (29 of 100), the lack of a statistically significant improvement is not unexpected. To the best of our knowledge, only two studies have used the FACE‐Q to evaluate patient‐reported outcomes following use of PRP or PRF monotherapy for facial rejuvenation 43,44 . In one study, Lee and colleagues showed improvement in participant satisfaction with overall facial appearance and cheeks following a single injection of PRF 43 while in the other study Nacopoulos and colleagues that reported an improvement in the satisfaction with skin questionnaire following several sessions of injectable PRF treatment 44 …”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Injectable platelet‐rich fibrin for facial rejuvenation: A prospective, single‐center study

Hassan

Quinlan

Ghanem

2020

J of Cosmetic Dermatology

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Injectable platelet‐rich fibrin for facial rejuvenation: A prospective, single‐center study

Hassan

Quinlan

Ghanem

2020

J of Cosmetic Dermatology

View full text Add to dashboard Cite

show abstract

“…Half of the acne scarring studies (4/8 = 50%) were classified as high quality, providing results from placebo-controlled, randomized, and blinded trials (Table 3). [48][49][50][51] Conversely, 57% (8/14) of aging facial skin studies [69][70][71][72][73][74][75][76] and 67% (6/9) of facial procedure studies [63][64][65][66][67] were graded as low-quality and moderatequality studies, respectively (Table 3).…”

Section: Other Aesthetic Applications Of Prpmentioning

confidence: 99%

The Efficacy of Platelet-Rich Plasma in the Field of Hair Restoration and Facial Aesthetics—A Systematic Review and Meta-analysis

Gupta

Versteeg

Rapaport³

et al. 2019

J Cutan Med Surg

View full text Add to dashboard Cite

As a promising alternative to traditional treatment, platelet-rich plasma (PRP) is being used to encourage hair growth through the release of growth factors and cytokines. In addition to hair restoration, PRP’s multifactorial capabilities can also be used to treat aging skin, facial scarring, and acne. The purpose of this review is to critically examine the success of PRP in the field of dermatology, with specific attention to the role of PRP in hair restoration. Where possible, meta-analyses were used to evaluate the efficacy of PRP. In androgenetic alopecia (AGA) patients, 3 monthly PRP injections (1 session administered every month for 3 months) exhibited greater efficacy over placebo as measured by change in total hair density (hair/cm2) over the treatment period (mean difference: 25.61, 95% CI: 4.45 to 46.77; P = .02). The studies included in the meta-analysis used a half-head design, which may have influenced the results because of the effects PRP can induce. Controlled studies suggest that 2 to 4 sessions of PRP combined with traditional therapies and procedures can help minimize acne scarring and facial burns, improve aesthetic results, and decrease recovery time. However, data for these indications are lacking and are less robust in design. In conclusion, to achieve an improvement in hair restoration in patients with mild AGA, 3 initial monthly PRP injections should be given. Only upon completion of rigorous, randomized, controlled studies can standardized and effective PRP protocols for treating dermatology conditions such as acne scarring, facial burns, and aging skin be determined.

show abstract

“…Clinical use of PRP injections has gained traction in plastic surgery, 12 maxillofacial surgery, 13 wound healing, 14 and dermatology. 15 In the practice of sports medicine, PRP injections have been used in the treatment of lateral epicondylitis, showing reduced rates of conversion to surgical treatment from medical management, 16 as well as marked improvement in visual analog scale (VAS) pain scale and tendon appearance on magnetic resonance imaging (MRI). 17 Furthermore, PRP has been shown to provide relief from pain and inflammation associated with OA, making it a therapeutic treatment in the management of OA.…”

mentioning

confidence: 99%

The Use of Platelet-Rich Plasma in Symptomatic Knee Osteoarthritis

et al. 2018

View full text Add to dashboard Cite

With average life expectancy and the rising prevalence of obesity, osteoarthritis (OA) is creating an increasingly large financial and physical burden on the U.S. population today. As the body ages and experiences trauma, articular cartilage surfaces in joints are gradually worn away, leading to OA. Traditionally, treatment options have included lifestyle modifications, pain management, and corticosteroid injections, with joint replacement reserved for those who have exhausted nonsurgical measures. More recently, hyaluronic acid, micronized dehydrated human amniotic/chorionic membrane tissue, and platelet-rich plasma (PRP) injections have started to gain traction. PRP has been shown to have both anti-inflammatory effects through growth factors such as transforming growth factor-β and insulin-like growth factor 1, and stimulatory effects on mesenchymal stem cells and fibroblasts. Multiple studies have indicated that PRP is superior to hyaluronic acid and corticosteroids in terms of improving patient-reported pain and functionality scores. Unfortunately, there are many variations in PRP preparation, and lack of standardization in factors, such as speed and duration of centrifugation, leads to wide ranges of platelet and leukocyte concentrations. This review examines the current literature addressing the use of PRP in symptomatic knee OA and addresses suggestions for future studies in this area.

show abstract

Platelet rich plasma for photodamaged skin: A pilot study

Abstract: A simple method of PRP preparation offers modest benefit in treating the effects of skin aging and photodamage. Future research studies should alter our methods using a stepwise approach to optimize the treatment of aging facial skin with PRP.

Cited by 37 publications

References 24 publications

Injectable platelet‐rich fibrin for facial rejuvenation: A prospective, single‐center study

Injectable platelet‐rich fibrin for facial rejuvenation: A prospective, single‐center study

The Efficacy of Platelet-Rich Plasma in the Field of Hair Restoration and Facial Aesthetics—A Systematic Review and Meta-analysis

The Use of Platelet-Rich Plasma in Symptomatic Knee Osteoarthritis

Contact Info

Product

Resources

About