Platelet-rich plasma and platelet-rich fibrin in periodontal regeneration: A review

Mohan, Sunil Paramel; Jaishangar, Nallusamy; Devy, Sandha; Narayanan, A. Shankar; Cherian, Deepthi; Madhavan, Sanupa S

doi:10.4103/jpbs.jpbs_41_19

Cited by 50 publications

(51 citation statements)

References 20 publications

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“… 65 As the second generation of platelet concentrate and a fully autologous biomaterial, platelet-rich fibrin (PRF) is easier to prepare and apply than PRP. 67 A retrospective study showed that in the bone augmentation surgery, the exposure rate with the group that solid advanced PRF (A-PRF) covering on the surface of titanium mesh (0.00%) is significantly less than that of the titanium mesh covered with the collagen membrane (23.5%; P < 0.05). 68 This result may be related to the initial clot stabilization mediated by the fibrin in PRF on the one hand.…”

Section: Surgical Management Of Titanium Mesh In Bone Augmentationmentioning

confidence: 99%

Titanium mesh for bone augmentation in oral implantology: current application and progress

et al. 2020

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Guided bone regeneration (GBR) is an effective and simple method for bone augmentation, which is often used to reconstruct the alveolar ridge when the bone defect occurs in the implant area. Titanium mesh has expanded the indications of GBR technology due to its excellent mechanical properties and biocompatibility, so that the GBR technology can be used to repair alveolar ridges with larger bone defects, and can obtain excellent and stable bone augmentation results. Currently, GBR with titanium mesh has various clinical applications, including different clinical procedures. Bone graft materials, titanium mesh covering methods, and titanium mesh fixing methods are also optional. Moreover, the research of GBR with titanium mesh has led to multifarious progresses in digitalization and material modification. This article reviews the properties of titanium mesh and the difference of titanium mesh with other barrier membranes; the current clinical application of titanium mesh in bone augmentation; common complications and management and prevention methods in the application of titanium mesh; and research progress of titanium mesh in digitization and material modification. Hoping to provide a reference for further improvement of titanium mesh in clinical application and related research of titanium mesh.

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Section: Surgical Management Of Titanium Mesh In Bone Augmentationmentioning

confidence: 99%

Titanium mesh for bone augmentation in oral implantology: current application and progress

et al. 2020

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“…Fatores bioativos como o L-PRF apresentam-se como um recurso importante para o manejo de grandes comunicações buco-sinusais, por permitir um microambiente propício ao reparo tecidual (He et al 2017;Mohan et al 2019), podendo ser associado a técnicas já preconizadas na literatura. Research, Society andDevelopment, v. 9, n. 10, e2359108502, 2020 (CC BY 4.0) | ISSN 2525-3409 | DOI: http://dx.doi.org/10.33448/rsd-v9i10.8502 A partir disso, planejamos utilizar um plug de L-PRF associado a uma membrana de L-PRF, isolados da cavidade oral por um retalho mucoperiosteal vestibular, para o manejo da comunicação buco-sinusal.…”

Section: Discussionunclassified

Fechamento cirúrgico de comunicação buco-sinusal com uso de L-PRF: um relato de caso

Macedo

Pereira

Barros

et al. 2020

RSD

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Introdução: A comunicação patológica entre a cavidade bucal e o seio maxilar, é uma sequela frequente de eventos traumáticos na região posterior da maxila. Os concentrados plaquetários, como o L-PRF, têm sido utilizados em diversas aplicações clínicas, dentre elas o manejo de comunicações buco-sinusais extensas. Objetivo: O presente relato de caso tem como objetivo descrever o fechamento cirúrgico de uma comunicação buco sinusal utilizando L-PRF associado a retalho vestibular. Relato de caso: Paciente do sexo feminino, melanoderma, tabagista, com histórico de sinusite crônica associada a halitose e secreção em cavidade oral há aproximadamente três anos, com início dos sintomas após exodontia de molar superior. Exame tomográfico mostrou defeito ósseo medindo cerca de 7 mm, comunicando a cavidade oral com o seio maxilar direito. Sob anestesia local, foi realizada exérese e debridamento do trajeto fistuloso. O defeito ósseo foi preenchido com as membranas de L-PRF fixadas abaixo do periósteo e, então, o retalho vestibular foi avançado e posto em posição para o completo fechamento da comunicação buco-sinusal. Em acompanhamento pós-operatório de 6 meses, a paciente não apresentou sinais clínicos ou radiográficos de sinusite maxilar e a tomografia computadorizada evidenciou o fechamento da comunicação buco-sinusal. Conclusão: O uso do L-PRF no manejo de comunicações buco-sinusais pode ser considerado uma alternativa a outras técnicas, com reparo adequado dos tecidos moles e potencial osséoindutor importante.

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“…There is a certain limitation of this approach; since there are no anticoagulants, the clinical success of this procedure is dependent on speedy blood collection and centrifugation well before the activation of clotting cascade. 39 It is reported that the fibrin clot is transformed into a membrane by compression between sterile gauzes. 40 Other noticeable disadvantages of the PRF included requirement of faster handling for prognosis and limited quantitative of autologous blood.…”

Section: Preparation Of Prfmentioning

confidence: 99%

Role of Platelet-Rich Fibrin (PRF) and Platelet-Rich Plasma (PRP) in Oro-Facial Tissue Regeneration: A Narrative Review

Deeb

2020

Journal of Advanced Oral Research

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Background and Aim: Regeneration potential of platelet-rich fibrin (PRF) and platelet-rich plasma (PRP) in oral tissues regeneration has revolutionized the clinical dentistry in recent years. The in vivo and in vitro research on PRP and PRF has opened a new avenue in the dentistry and medicinal care. It is a minimally invasive and cost-effective technique that will raise the bar of clinical dentistry. The results presently documented are overwhelming; the potential to use PRF and PRP in the clinical dentistry have improved dental quality, satisfaction, and clinical outcome. The aim of the review was to recapitulate the regenerative and healing potential of platelet extracts in different disciplines of clinical dentistry. Materials and Methods: The attempt was to answer the following question: what are the various clinical oral health applications for PRF and PRP available in the published literature? The dual functions (tissue sealants and drug delivery systems to carry biomolecules and chemotactic growth factors) have helped the practitioners to treat the complicated oral conditions and tissues regeneration. The PRF and plasma has emerged as a powerful therapeutic tool for management of soft and hard tissue healing and regenerative procedures, including implant osseointegration. More research is mandatory to use these platelets concentrate to their full potential in various clinical applications. Conclusion: PRF is an emerging therapeutic tool in the management of oral soft and hard tissue healing and regenerative procedures.

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Platelet-rich plasma and platelet-rich fibrin in periodontal regeneration: A review

Cited by 50 publications

References 20 publications

Titanium mesh for bone augmentation in oral implantology: current application and progress

Titanium mesh for bone augmentation in oral implantology: current application and progress

Fechamento cirúrgico de comunicação buco-sinusal com uso de L-PRF: um relato de caso

Role of Platelet-Rich Fibrin (PRF) and Platelet-Rich Plasma (PRP) in Oro-Facial Tissue Regeneration: A Narrative Review

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