Platelet-Rich Fibrin in Third Molar Surgery: Systematic Review and Meta-Analysis Protocol

Salas, Gaston A.; Lai, Shuheng; Verdugo-Paiva, Francisca; Requena, Roberto A.

doi:10.1177/19433875211016203

Cited by 2 publications

(2 citation statements)

References 17 publications

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“…Third molar eruption occurs most commonly between the ages of 17 and 26 [1]. Third molars are either partially erupted or fail to erupt completely, with a prevalence rate of 22.63 % globally [2].…”

Section: Introductionmentioning

confidence: 99%

Efficacy of Hydrocortisone, Povidone-Iodine, and Normal Saline as an Irrigating Solution During Surgical Removal of Impacted Mandibular Third Molars: A Randomized Controlled Trial

Ahmed,

Baliga,

Baliga

et al. 2024

Cureus

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BackgroundThe surgical removal of mandibular third molars is one of the most common procedures in dentistry. Researchers have extensively studied the treatment of postoperative sequelae such as pain, edema, trismus, and alveolar osteitis throughout the past six decades. Many approaches have been used to address clinical difficulties after third molar surgery, including various flap designs and irrigating solutions. The aim of this study was to compare the effects of three irrigating solutions, hydrocortisone, povidone-iodine, and normal saline, on pain, trismus, and edema following surgical removal of the impacted mandibular third molar. MethodologyThe study involved 105 participants who required surgical extraction of mandibular third molars. The patients' ages ranged from 18 to 40 years, and they fulfilled the inclusion criteria. Using a simple random sampling technique, they were divided into three groups (group 1: hydrocortisone, group 2: povidoneiodine, group 3: normal saline). The parameters evaluated were edema, pain, and trismus on the second and seventh postoperative days. All data were input into Microsoft Excel (Microsoft ® Corp., Redmond, USA) worksheets and analyzed using Stata 17.0 (StataCorp LLC, College Station, USA). The visual analog scale (VAS) score was used to measure postoperative pain, and postoperative swelling was measured using linear measurements from four fixed anatomical points and compared to preoperative values. To assess trismus, the inter-incisal distance was measured in millimeters with a caliper. A p-value of <0.01 was considered statistically significant. ResultsThe mean VAS score for pain in group 1 was lower than the other two groups. The effect of group 1 was significant on the second postoperative day but insignificant on the seventh postoperative day for swelling. The effect of all three groups on trismus was significant on the second and seventh days. ConclusionsHydrocortisone as an irrigating solution showed promising results in managing postoperative swelling in the first 48 hours, but its effect gradually declined by the seventh postoperative day. Additionally, it was effective in controlling postoperative pain and trismus. This suggests that utilizing hydrocortisone as an irrigating solution, compared to povidone-iodine, has been proven to be a significantly effective option in reducing postoperative pain, edema, and trismus resulting from the surgical removal of impacted teeth.

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Section: Introductionmentioning

confidence: 99%

Efficacy of Hydrocortisone, Povidone-Iodine, and Normal Saline as an Irrigating Solution During Surgical Removal of Impacted Mandibular Third Molars: A Randomized Controlled Trial

Ahmed,

Baliga,

Baliga

et al. 2024

Cureus

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show abstract

“…Third molars, popularly known as wisdom teeth, represent the last teeth to develop in the human dental arch, typically erupting between the ages of 16 and 27 [1]. Despite their original function in chewing, their presence often associates with complications, generating a flow of patients in dental offices reporting painful complaints in the posterior region of the jaws.…”

Section: Introductionmentioning

confidence: 99%

Como o uso de fibrina rica em plaquetas pode beneficiar as exodontias de terceiros molares mandibulares?

Lima,

Coutinho,

Viana

et al. 2024

Braz. Journ. Dentistry Oral Rad.

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Surgery for the removal of third molars is a surgical procedure commonly performed in Dentistry. It is associated with inflammatory events and possible complications, being more evident after the removal of lower molars, since in most cases there is a need for more invasive approaches. It is essential for the dentist to minimize such effects, providing a more peaceful postoperative period with less morbidity for the patient. In this context, platelet-rich fibrin (PRF) was developed, which is considered a platelet aggregate obtained by centrifugation of the patient's own blood and proposes to minimize inflammatory effects, accelerate healing and repair processes, and reduce postoperative complications. A literature review on the effect of L-PRF in sockets after the removal of mandibular third molars was conducted, evaluating its efficacy on pain, swelling, trismus, and healing. A bibliographic survey was performed on the PubMed, Web of Science, and Elsevier databases, using the following descriptors: 'platelet rich fibrin', 'third molar', and 'surgery', limiting to articles written in English published from 2013 to 2023. Thus, we have a current scientific overview of the real effect of using this platelet aggregate in the extraction of lower third molars. The studies reviewed, for the most part, showed positive results in improving pain, swelling, trismus, and healing.

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Platelet-Rich Fibrin in Third Molar Surgery: Systematic Review and Meta-Analysis Protocol

Cited by 2 publications

References 17 publications

Efficacy of Hydrocortisone, Povidone-Iodine, and Normal Saline as an Irrigating Solution During Surgical Removal of Impacted Mandibular Third Molars: A Randomized Controlled Trial

Efficacy of Hydrocortisone, Povidone-Iodine, and Normal Saline as an Irrigating Solution During Surgical Removal of Impacted Mandibular Third Molars: A Randomized Controlled Trial

Como o uso de fibrina rica em plaquetas pode beneficiar as exodontias de terceiros molares mandibulares?

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