Platelet Dysfunction in Children with AIDS † 642

Ddavp Is Not a Panacea for Children With Bleeding Disorders

“…Platelet dysfunction characterized by prolonged bleeding time and impaired ATP release and platelet aggregation following arachidonic acid and collagen is frequent in children with AIDS. The risk of bleeding may be minimized by administration of DDAVP before an invasive procedure or surgery ( Abdullah et al , 1998 ).…”