Platelet Count Neither Decreases nor Relates to Blood Glucose Level

Abstract

There are abnormalities of hemostasis and rheologic properties in uncontrolled diabetics that could well be involved in the pathogenesis of diabetic microangiopathy and macroangiopathy (1). Platelets from diabetic patients showed increased aggregation when measured in whole blood. This phenomenon seems to be mediated by erythrocytes because normal platelets became hyperaggregable in the presence of "diabetic" erythrocytes (1). According to the study of Kaplar and colleagues in type 2 diabetes, a non-significant, but remarkable, tendency between elevation of postprandial serum glucose levels and platelet-monocyte aggregate formation was observed (2). However, Petersen and Gormsen reported no significant differences could be demonstrated in platelet aggregation between the normal controls and the patients with diabetes mellitus (3). Concerning the platelet quantity, some previous reports (4,5) documented decreased platelets in diabetic patients while the other reported the opposite observation (6).Here we studied the correlation between the platelet count and the blood sugar levels in 40 healthy Thai subjects. Blood samples from each

Platelet mean volume, distribution width, and count in type 2 diabetes, impaired fasting glucose, and metabolic syndrome: a meta‐analysis

“…Moreover, one study included only IGT subjects . Therefore, 39 unique studies were included in the meta‐analysis. Studies characteristics, references, and NOS scores are provided in Table and Supporting Information Table S1 and S2.…”