Abstract:Introduction: The Aeson bioprosthetic total artificial heart (ATAH) is a pulsatile and autoregulated device. The aim of this study was to evaluate the level of platelet activation secondary to ATAH implantation. Methods: We examined the level of platelet activation markers in adult patients receiving ATAH support (n=16) during clinical follow up by quantifying sPselectin (sPsel) and sCD40L in plasma. Results: The cumulative duration of ATAH support was 3587 days. Before implantation, sCD40L was 2684.6 pg/mL (9… Show more
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