Plasticity of the superior olivary complex

Consequences of unilateral hearing loss: Time dependent regulation of protein synthesis in auditory brainstem nuclei

“…The effects of CA or CHL on the cochlear nucleus can be dramatic, yet variable depending upon the species, the developmental state at the time of manipulation, and the type of manipulation performed (see Tucci and Rubel, 2005;Illing et al, 2000). Previous studies using conductive hearing impairment as a model to examine deprivation have described changes that are either similar to CA (e.g., Webster and Webster, 1977;Coleman and O'Connor, 1979;Webster, 1983c;Blatchley et al, 1983), or show virtually no structural changes at all (e.g., Born et al, 1991;Doyle and Webster, 1991;Tucci and Rubel, 1985;Tucci et al, 1987).…”

A Comparison of the Brainstem Auditory Evoked Response in Healthy Ears of Unilaterally Deaf Dogs and Bilaterally Hearing Dogs

“…The skull sizes of the dogs undergoing the BAER examination in this study were not recorded, but the results were compared between dogs of the same breed and the same age. Illing et al reported that the superior olivary complex, a wave III generator in humans, showed signs of auditory plasticity, responding to hearing impairment by expressing plasticity-related substances (Illing et al 2000). Popelar et al found that amplitudes of evoked potentials increased over a course of three weeks in adult guinea pigs whose hair cells were destroyed (Popelar et al 1994).…”

Hearing disorders in brainstem lesions

“…The superior olivary complex is the initial station of the binaural signal integration (Illing et al, 2000;Moore, 2000;Yin, 2002), thus a unilateral lesion may result in impairment of interaural time and level differences and sound localization (Table 29.4). Levine et al (1993) reported isolated demyelinating lesions of the superior olivary complex in MS.…”