Plasmonic Tweezers towards Biomolecular and Biomedical Applications

Xue, Hong; Sun, Changsen

doi:10.3390/app9173596

Cited by 11 publications

(5 citation statements)

References 101 publications

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“…In particular, the so called selfinduced back-action (SIBA) trapping, inspired by the concept of optomechanics, has been demonstrated. [64,65] While extensive details on plasmonic tweezers can be found in recently published This can be well fitted with a single exponential function, where P 0 and A are constants, and P 0 is the trapping probability without illumination. The error bars represent the relative deviation.…”

Section: Plasmonic Nanocavities For Single-molecule Manipulationmentioning

confidence: 99%

Plasmonic Nanoarchitectures for Single‐Molecule Explorations: An Overview

Koya

2021

Advanced Photonics Research

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Plasmonic nanostructures have immense potentials for extreme concentration of light into deep‐subwavelength spaces with giant local field intensity, which can be exploited for novel applications including nanoscale optical trapping, biosensing, and enhanced spectroscopy. Herein, a succinct overview of the potentials of engineered plasmonic nanoarchitectures of various geometries including nanoparticles, nanodimers, nanoapertures, nanoporous surfaces, and picometer‐scale gap systems for single‐molecule analysis is provided. In particular, the potentials of single plasmonic nanoparticles for single‐molecule sensing, coupled plasmonic nanodimers for few‐molecule strong coupling, metallic nanocavities for optical manipulation of single molecules, nanoporous metasurfaces for enhanced single‐molecule spectroscopy, and plasmonic picocavities for single‐molecule optomechanics are extensively discussed. Finally, as an outlook, exploiting such novel nanoarchitectures for developing innovative biosensing platforms that will be able to trap and detect objects at the single‐molecule level is forwarded.

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Section: Plasmonic Nanocavities For Single-molecule Manipulationmentioning

confidence: 99%

Plasmonic Nanoarchitectures for Single‐Molecule Explorations: An Overview

Koya

2021

Advanced Photonics Research

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“…99 A metal nanoparticle or metal thin layer is illuminated with light to cause surface plasmon resonance (SPR), which generates an intense electromagnetic field near the metal surface. An optical force induced by the electromagnetic field is expressed by: 100,101 〈Foe〉 = ∫∂V 〈T(r, t)〉nda (11) where ∂V is the surface of a volume enclosing an irradiated structure and T is the Maxwell stress tensor. When a particle radius, a, is smaller than the wavelength and the length of the electromagnetic field, the particle is regarded as a point dipole, and the optical gradient force (FPOT) becomes dominant:…”

Section: •5 Plasmonic Optical Tweezersmentioning

confidence: 99%

Particle Manipulation with External Field; From Recent Advancement to Perspectives

Miyagawa

Okada

2020

ANAL. SCI.

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Physical forces, such as dielectric, magnetic, electric, optical, and acoustic force, provide useful principles for the manipulation of particles, which are impossible or difficult with other approaches. Microparticles, including polymer particles, liquid droplets, and biological cells, can be trapped at a particular position and are also transported to arbitrary locations in an appropriate external physical field. Since the force can be externally controlled by the field strength, we can evaluate physicochemical properties of particles from the shift of the particle location. Most of the manipulation studies are conducted for particles of sub-micrometer or larger dimensions, because the force exerted on nanomaterials or molecules is so weak that their direct manipulation is generally difficult. However, the behavior, interactions, and reactions of such small substances can be indirectly evaluated by observing microparticles, on which the targets are tethered, in a physical field. We review the recent advancements in the manipulation of particles using a physical force and discuss its potentials, advantages, and limitations from fundamental and practical perspectives.

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“…Passive focusing techniques, such as deterministic lateral displacement [4,5] and inertial microfluidics [6,7], have the advantages of low cost and high throughput, but require high structural dimensional accuracy and offer limited flexibility. Active focusing techniques include dielectrophoresis [8,9], magnetophoresis [10,11], optical tweezer [12,13] and surface acoustic waves (SAWs) [14,15]. With the help of external force fields, precise manipulation of particles can be achieved.…”

Section: Introductionmentioning

confidence: 99%

High throughput particle sorting based on traveling surface acoustic wave (TSAW) is realized by coupling spiral microchannel and a novel arc electrode

wang

Ji²,

Liu³

et al. 2023

Phys. Scr.

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Acoustofluidic technology is an ideal tool for biomedical applications. However, the sorting performance and flux of acoustofluidic chips cannot be achieved simultaneously. In this paper, we propose a method for coupling a novel arc gold interdigital transducer (IDT) with a spiral microchannel. A spiral microchannel is used to focus the target particle (20 µm) inertially to improve the sorting efficiency of the chip. The channel uses a Y-shaped inlet to bind small particles (5 μm) in a fixed stream beam to improve the sorting efficiency of the chip. The fit of arc electrode and spiral flow channel enlarges the acoustic control area, so that the target particles can still be separated effectively at high flow velocity. The results show that when the signal source frequency is 33.7 MHz and the voltage is 5 V, the designed chip can effectively separate the target particles at the flow rate of 25-65 µL/min, and the sorting purity is 100%. The sorting efficiency decreased with the increase of flow rate, 25 µL/min: 100%, 35 µL/min: 100%, 45 µL/min: 94.8% (within 1.2% error), 55 µL/min: 92% (within 1% error), 65 µL/min: 83.4% (within 2.4% error). This chip provides an idea for achieving high throughput, high purity and high efficiency cell sorting.

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Plasmonic Tweezers towards Biomolecular and Biomedical Applications

Cited by 11 publications

References 101 publications

Plasmonic Nanoarchitectures for Single‐Molecule Explorations: An Overview

Plasmonic Nanoarchitectures for Single‐Molecule Explorations: An Overview

Particle Manipulation with External Field; From Recent Advancement to Perspectives

High throughput particle sorting based on traveling surface acoustic wave (TSAW) is realized by coupling spiral microchannel and a novel arc electrode

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