Plasmonic nano-aperture label-free imaging (PANORAMA)

Abstract

Label-free optical imaging of nanoscale objects faces fundamental challenges. Techniques based on propagating surface plasmon resonance (SPR) and localized surface plasmon resonance (LSPR) have shown promises. However, challenges remain to achieve diffraction-limited resolution and better surface localization in SPR imaging. LSPR imaging with dark-field microscopy on metallic nanostructures suffers from low light throughput and insufficient imaging capacity. Here we show ultra-near-field index modulated PlAsmonic NanO-apeRture lAbel-free iMAging (PANORAMA) which uniquely relies on unscattered light to detect sub-100 nm dielectric nanoparticles. PANORAMA provides diffraction-limited resolution, higher surface sensitivity, and wide-field imaging with dense spatial sampling. Its system is identical to a standard bright-field microscope with a lamp and a camera – no laser or interferometry is needed. In a parallel fashion, PANORAMA can detect, count and size individual dielectric nanoparticles beyond 25 nm, and dynamically monitor their distance to the plasmonic surface at millisecond timescale.

Thermal Stability and Kinetics of Single I2@ZIF-8 Particles

“…The main reason for this phenomenon is attributed to the balance between the refractive-index increase and optical loss generated from the filling of I 2 . The introduction of certain I 2 will enhance the mass and refractive index of porous ZIF-8, which results in a strong light scattering based on Mie scattering theory . However, such an effect is not significant in I 2 @ZIF-8 particles with a larger q value, and the strong optical absorption of I 2 in the visible light region causes the decrease of RGB values (Figure d and Figure S7).…”

Flexible SERS Substrate with a Ag–SiO2 Cosputtered Film for the Rapid and Convenient Detection of Thiram

“…The small shift is usually attributed to the different Ag nanoparticle sizes . For the 90 s deposited film, a peak at 660 nm was also observed in addition to the peak around 450 nm, which indicated the SPR characteristics of a continuous film …”

Plasmonic metamaterial based virus detection system: a review

“…There has been a study of apple stem pitting virus (ASPV) by imaging the aptamer binding with the coat protein using SPR Lautner et al (2010). Recently, researchers have achieved sub-100nm resolution using this technique Ohannesian et al (2020) which can be applied for virus detection as well.…”