Plasmonic and chiroplasmonic nanobiosensors based on gold nanoparticles

Sharifi, Majid; Hosseinali, Sara Haji; Alizadeh, Reza; Hasan, Anwarul; Attar, Farideh; Salihi, Abbas; Shekha, Mudhir Sabir; M-Amen, Karwan; Aziz, Falah Mohammad; Saboury, Ali Akbar; Akhtari, Keivan; Taghizadeh, Akbar; Hooshmand, Nasrin; El‐Sayed, Mostafa A.; Falahati, Mojtaba

doi:10.1016/j.talanta.2020.120782

Cited by 57 publications

(36 citation statements)

References 165 publications

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“…On the other hand, some limitations in targeted drug delivery 13 result in severe toxicity to liver, kidney and spleen [13][14][15] , as well as the poor distribution of anti-cancer drugs in tumor site 6,16 . Therefore, several strategies like development of some NP-based platforms for targeted drug delivery have been reported 4,17,18 . In this regard, it has been well documented that protein coating of NPs can enhance active absorption of a loaded drug by the tumor cells via protein receptors 19,20 .…”

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confidence: 99%

Combined chemo-magnetic field-photothermal breast cancer therapy based on porous magnetite nanospheres

Sharifi

Hasan

Nanakali

et al. 2020

Sci Rep

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The efficacy of different modalities of treating breast cancer is inhibited by several limitations such as off-targeted drug distribution, rapid drug clearance, and drug resistance. To overcome these limitations, we developed Lf-Doxo-PMNSs for combined chemo-MF-PTT. The PMNSs were synthesized by hydrothermal method and their physicochemical properties were examined by FE-SEM, TEM, DLS, TGA, XRD investigations. The cytotoxicity of as-synthesized NPs against 4T1 cells was carried out by MTT and flow cytometry assays. Afterwards, the anti-cancer activities of as-synthesized Lf-Doxo-PMNSs on the tumor status, drug distribution and apoptosis mechanism were evaluated. The anti-cancer assays showed that Lf-Doxo-PMNSs significantly suppressed the cancer cell proliferation and tumor weight by prolonging drug availability and potential drug loading in tumor cells; whereas they showed a minimum cytotoxicity against non-cancerous cells. Likewise, combined chemo-MF-PTT using Lf-Doxo-PMNSs displayed the highest anti-cancer activity followed by combined chemo-PTT and combined chemo-MF therapy based on altering the apoptosis mechanism. Therefore, these results showed that combined chemo-MF-PTT based on Lf-Doxo-PMNSs can be used as a promising therapeutic platform with potential targeted drug delivery and high loading capacity features as well as reducing cancer drug resistance.

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confidence: 99%

Combined chemo-magnetic field-photothermal breast cancer therapy based on porous magnetite nanospheres

Sharifi

Hasan

Nanakali

et al. 2020

Sci Rep

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“…However, as mentioned earlier, the first use of nanomaterials in the detection of viruses in the late 1990s was used to detect human papillomavirus [ 93 ]. Today, various types of organic and inorganic nanomaterials, especially AuNPs, magnetic NPs, and carbon-based NPs with biomolecular compounds loaded on them (for instance, nucleic acid, antibodies, antigens, or capsid peptides) for diagnosis viruses have been used [ 94 , 95 ]. One of the most important advantages of using nanomaterials compared to the methods mentioned above is the possibility of using several probes simultaneously with biological and non-biological labels in detecting viruses [ 96 ].…”

Section: Application Of Nanobiosensors In Covid-19 Detectionmentioning

confidence: 99%

“…Briefly, a biosensor can be defined as a bio-receptor for measurement, and a signal transducer for the production of physical signals such as optical, electrical, thermal, and mechanical from biological changes [ 32 , 33 ]. In this regard, the biosensor needs to be independent of physical parameters such as temperature and pH.…”

Section: Introductionmentioning

confidence: 99%

“…In addition to these two methods, the use of thermal and mechanical nanobiosensors has also been effective in detecting immunogenic agents resulting in microbial activity [ 39 ]. In general, the advantages of nanobiosensors-based diagnostic methods over conventional methods are: low cost; reproducibility; rapid Measurements; reusable; suitable for placement of enzymes; no need for calibration; appropriate for mass production; possibility of miniaturization; reducing power consumption due to voltage reduction; enabled label-free recognition; upper signal-to-noise ratio [ 32 , 33 , 35 ].…”

Section: Introductionmentioning

confidence: 99%

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Rapid diagnostics of coronavirus disease 2019 in early stages using nanobiosensors: Challenges and opportunities

Sharifi

Hasan

Haghighat

et al. 2021

Talanta

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The rapid outbreak of coronavirus disease 2019 (COVID-19) around the world is a tragic and shocking event that demonstrates the unpreparedness of humans to develop quick diagnostic platforms for novel infectious diseases. In fact, statistical reports of diagnostic tools show that their accuracy, specificity and sensitivity in the detection of COVID-face challenges that can be eliminated by using nanoparticles (NPs). In this study, we aimed to present an overview on the most important way to diagnose different kinds of viruses followed by the introduction of nanobiosensors. Afterward, some methods of coronavirus detection such as imaging, laboratory and kit-based diagnostic tests are surveyed. Furthermore, nucleic acids/protein- and-immunoglobulin (Ig)-based nanobiosensors for the COVID-19 detection infection are reviewed. Finally, current challenges and future perspective for the development of diagnostic or monitoring technologies in the control of COVID-19 are discussed to persuade the scientists in advancing their technologies beyond imagination. In conclusion, it can be deduced that as rapid COVID-19 detection infection can play a vital role in disease control and treatment, this review may be of great help for controlling the COVID-19 outbreak by providing some necessary information for the development of portable, accurate, selectable and simple nanobiosensors.

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“…The red-shift of surface plasmon resonance peak indicated the crystal growth of Au nanoparticles from Au nanoseeds. It is widely accepted that the optical properties of AuNSps are highly dependent on the nanoparticle diameter [19]. Smaller nanospheres primarily absorb light and have absorption peaks near 520 nm, while larger spheres exhibit light scattering and have significantly broaden and red-shifted absorption peaks.…”

Section: Synthesis Of Aunspsmentioning

confidence: 99%

Potential Application of Gold Nanospheres as a Surface Plasmon Resonance Based Sensor for In-Situ Detection of Residual Fungicides

Nhat

Phong

Nguyen

et al. 2020

Sensors

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It is essential to develop a simple and sensitive method to rapidly detect residual fungicides in agricultural products to protect human health. So far, little studies have been reported on potential application of gold nanospheres (AuNSps) as a surface plasmon resonance based sensor for in-situ detection of residual fungicides. Therefore, in this study, we investigated the potential application of AuNSps as a surface plasmon resonance based sensor for in-situ detection of fungicides. AuNSps were successfully synthesized via a seed-mediated method with some modifications. Firstly, gold nanoseeds were made during the reduction of chloroauric acid by trisodium citrate dihydrate (TSC). Then, AuNSps were grown from the seeds by using HAuCl 4 , TSC and EDTA. AuNSps were subsequently dropped on a glass substrate before covered by thiophanate methyl, a broad-spectrum systemic fungicide. The AuNSps coated glass substrate was subsequently dried in the air for further surface-enhanced Raman spectroscopy (SERS) measurements. Optical properties, shape and size of AuNSps were confirmed by UV-vis spectroscopy, XRD, SEM-EDX and TEM. The results showed that AuNSps were successfully synthesized with the size of 53 nm, and their resonance peak was located at 560 nm. The Raman signal intensity of thiophanate methyl covered on AuNSps is higher than that without AuNSps, indicating SERS effects of AuNSps deposited glass substrate.

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Plasmonic and chiroplasmonic nanobiosensors based on gold nanoparticles

Cited by 57 publications

References 165 publications

Combined chemo-magnetic field-photothermal breast cancer therapy based on porous magnetite nanospheres

Combined chemo-magnetic field-photothermal breast cancer therapy based on porous magnetite nanospheres

Rapid diagnostics of coronavirus disease 2019 in early stages using nanobiosensors: Challenges and opportunities

Potential Application of Gold Nanospheres as a Surface Plasmon Resonance Based Sensor for In-Situ Detection of Residual Fungicides

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