Plasmid-mediated drug resistance of shigellae in Kuwait

Td, Chugh; Suheir, A.; Mahboob, Amjad; Neil, L.; Elbishbishi, E.A.

doi:10.1007/bf02310016

Cited by 5 publications

(2 citation statements)

References 13 publications

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“…to antibacterial drugs has been reported from different parts of the world and is increasing [5]. First observed in S. flexneri in Japan [6], the development of transferable multi-drug resistance was soon reported elsewhere, including Taiwan [4], and was also observed in other shigellae [7]. In spite of the prevalence of shigellosis in Taiwan, there have been few epidemiological studies, and resistance patterns in this area have not as yet been investigated.…”

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confidence: 99%

Drug resistance and plasmid profile of shigellae in Taiwan

Lin

Chang

1992

Epidemiol. Infect.

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SUMMARYOne hundred and twenty-eight shigella strains isolated from newborn and infant human faecal specimens at Kaohsiung Medical College Hospital in Taiwan were serogrouped, serotyped and examined for drug-resistance patterns and for the presence of plasmids. Forty-seven per cent of the isolates were found to belong to the Shigella sonnei serogroup, 41 % to the S. fiexneri group, 9 % to the S. boydii group and 3 % to the S. dysenteriae group. The serotype with the greatest number of strains was S. sonnei I. (29 %) followed by S. flexneri 1 (27%). Each strain was tested for resistance to 11 antimicrobial agents. Eighty-eight per cent of the strains were resistant to tetracycline, 87 % to chloramphenicol, 84 % to streptomycin, 52% to ampicillin, 25 % to nalidixic acid, 29% to kanamycin, 11 % to cephalothin, 11 % to neomycin, 10 % to cotrimoxazole, 1 % to amikacin and none to gentamicin. The most prevalent resistance pattern was Ap Cm Sm Tc (28%). Clinical isolates demonstrating multiple resistance were found to harbour a large transmissible plasmid of 45-75 MDa while isolates without multiple resistance did not. Two large virulence plasmids of 123 and 110 MDa were found in 12 strains of S. flexneri and 4 strains of S. sonnei phase I. Small plasmids of 4-5, 4 2, 3 5, 2 8, 2-5. 2 0 and 1P5 MDa were also present in all strains. These small plasmids were species specific and can be used as marker plasmids to identify species.

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Section: Introductionmentioning

confidence: 99%

Drug resistance and plasmid profile of shigellae in Taiwan

Lin

Chang

1992

Epidemiol. Infect.

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“…The differences in resistance were seen in the case of erythromycin, chloramphenicol, streptomycin and tetracycline. 1286 salmonellae are known to ferment lactose, in this aspect Chugh., (1978) suggested that this characteristic found in these Salmonella is attributed to Lac + plasmid either as a separate entity or in conjunction with drug resistance. Chander et al (1980) suggested that certain Salmonella serotypes viz.…”

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Lactose Fermenting Salmonella Typhimurium, Salmonella Stratford and Salmonella Blegdam

Alexan

2017

Egyptian Journal of Agricultural Research

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he general concept that lactose fermenting Salmonella (lac+ Salmonella) are rare may be correct; however, these strains can become endemic in a given geographic area. Failure to detect these strains presents a public health problem.This study report cases of lactose fermenting Salmonella Typhimurium (4 isolates), Salmonella Stratford (2 isolates) isolated from diarrheic calves and S.Blegdam (one isolate) isolated from diseased chicken. The strains are strong lactose fermenter and resemble Escherichia coli on primary plating media and in triple sugar iron agar.The aim of this study was to compare the capacity of 4 different selective media:-Xylose Lysine Desoxycholate agar (XLD), novobiocin -brilliant green -glucose agar (NBG), modified semisolid Rappaport -Vassiliadis agar (MSRV) and Bismuth sulphite agar (BS) to detect the growth of lactose fermenting S. Typhimurium, S. Stratford and S.Blegdam inoculated in milk replacer. They were cultured, in parallel, on these media, both by direct cultivation and after selective enrichment in selenite broth. The performance of BS was the excellent medium of all media used followed by XLD in combination with lysine iron agar (LIA). On MSRV only two strains grew and only one produced swarming. On NBG after 48h in the cases where there was growth, the number of colonies was much lower and the rest were inhibited. Antibiotic sensitivity pattern differed between lactose -positive Salmonella isolates and lactose-negative Salmonella Typhimurium standard strain ATCC 14028. Lactose-positive strains showed higher degree of resistance than lactose-negative strain. The differences in resistance were seen in the case of erythromycin, chloramphenicol, streptomycin and tetracycline. 1286 salmonellae are known to ferment lactose, in this aspect Chugh., (1978) suggested that this characteristic found in these Salmonella is attributed to Lac + plasmid either as a separate entity or in conjunction with drug resistance. Chander et al. (1980) suggested that certain Salmonella serotypes viz.

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Monitoring of antibiotic resistance in Shigellae isolated in the Netherlands 1984–1989

Voogd

Schot

Leeuwen

et al. 1992

Eur. J. Clin. Microbiol. Infect. Dis.

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During surveillance of antimicrobial resistance in Shigella strains isolated in the Netherlands from 1984 to 1989 and forwarded to the National Institute of Public Health and Environmental Protection for typing, sensitivity to twelve antimicrobial agents was assessed. High rates of resistance to the older drugs of choice in treating shigellosis were found, i.e. ampicillin and trimethoprim-sulfamethoxazole. Ampicillin resistance varied from 33 to 53% among Shigella flexneri strains and from 10 to 17% among Shigella sonnei strains. Trimethoprim and trimethoprim-sulfamethoxazole resistance increased from 8% to about 25% among Shigella flexneri and from 16 to 46% among Shigella sonnei isolates. All strains were susceptible to the newer quinolones, but five strains resistant to nalidixic acid showed decreased susceptibility to norfloxacin. Approximately 10% of the isolates were resistant to the combination of ampicillin, trimethoprim and sulfamethoxazole.

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Plasmid-mediated drug resistance of shigellae in Kuwait

Cited by 5 publications

References 13 publications

Drug resistance and plasmid profile of shigellae in Taiwan

Drug resistance and plasmid profile of shigellae in Taiwan

Lactose Fermenting Salmonella Typhimurium, Salmonella Stratford and Salmonella Blegdam

Monitoring of antibiotic resistance in Shigellae isolated in the Netherlands 1984–1989

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