Plasmas for medicine

Woedtke, Th. von; Reuter, Stephan; Masur, Kai; Weltmann, Klaus‐Dieter

doi:10.1016/j.physrep.2013.05.005

Cited by 749 publications

(644 citation statements)

References 295 publications

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“…5) is that with the present device a higher power conversion into the "effluent" and accordingly into the production of reactive species for the plasma medical application [1,4] can be achieved by increasing the operation frequency. At this point, the individual challenges of this field of application has to be considered.…”

Section: -P3mentioning

confidence: 95%

“…Cold atmospheric pressure plasma jets cover a wide range of potential applications, e.g., plasma medicine, where these devices offer a high potential for therapeutic use [1]. While the basic research on biological effects in this field is meanwhile well established, the physics of the plasma sources itself must be well understood in order to explain the treatment effects and to address safety issues [2,3].…”

Section: Introductionmentioning

confidence: 99%

“…In plasma medicine, the aspect of efficacy is yet a topic for discussion, since the classification of effective agents is difficult due the variety, the individual response of the treated object, and the difficulties to measure them [1,4]. Especially in the case of plasma jets, the "effluent" that interacts with the surface is not identical with the "core" plasma in the ignition zone.…”

Section: Introductionmentioning

confidence: 99%

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Power measurement for an atmospheric pressure plasma jet at different frequencies: distribution in the core plasma and the effluent

Gerling

Brandenburg

Wilke

et al. 2017

Eur. Phys. J. Appl. Phys.

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Abstract. The characterization of electrical power distribution in an atmospheric pressure plasma jet operated at six different frequencies is investigated by measurement of input power and voltage-charge plots for the core plasma and the plasma in the effluent. The frequency change is further characterized by measuring the temperature in the effluent at different positions and input power levels. The power input into the core plasma is limited to about 1 W for a wide range of frequencies while the total input power and thus the power input into the effluent increases continuously with frequency.

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Section: -P3mentioning

confidence: 95%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Power measurement for an atmospheric pressure plasma jet at different frequencies: distribution in the core plasma and the effluent

Gerling

Brandenburg

Wilke

et al. 2017

Eur. Phys. J. Appl. Phys.

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“…Applications stemming from the interactions of plasmas and liquids include biomedicine and biological disinfection [3][4][5][6][7][8], chemical disinfection [9][10][11], and agricultural uses [12,13]. To most effectively utilize plasma-liquid systems requires a fundamental knowledge of their behavior; many researchers are now actively contributing to that knowledge through both experimental [1][2][14][15][16][17][18][19] and modelling efforts [20][21][22][23].…”

Section: Introductionmentioning

confidence: 99%

Fully coupled simulation of the plasma liquid interface and interfacial coefficient effects

Lindsay¹,

Graves²,

Shannon³

2016

J. Phys. D: Appl. Phys.

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There is a growing interest in the study of coupled plasma-liquid systems because of their applications to biomedicine, biological and chemical disinfection, agriculture, and other areas. Optimizing these applications requires a fundamental understanding of the coupling between phases. Though much progress has been made in this regard, there is still more to be done. One area that requires more research is the transport of electrons across the plasma-liquid interface. Some pioneering works (Rumbach et al 2015 Nat. Commun. 6, Rumbach et al 2015 J. Phys. D: Appl. Phys. 48 424001) have begun revealing the near-surface liquid characteristics of electrons. However, there has been little work to determine the near-surface gas phase electron characteristics. Without an understanding of the near-surface gas dynamics, modellers are left to make assumptions about the interfacial conditions. For instance it is commonly assumed that the surface loss or sticking coefficient of gas-phase electrons at the interface is equal to 1. In this work we explore the consequences of this assumption and introduce a couple of ways to think about the electron interfacial condition. In one set of simulations we impose a kinetic condition with varying surface loss coefficient on the gas phase interfacial electrons. In a second set of simulations we introduce a Henry's law like condition at the interface in which the gas-phase electron concentration is assumed to be in thermodynamic equilibrium with the liquid-phase electron concentration. It is shown that for a range of electron Henry coefficients spanning a range of known hydrophilic specie Henry coefficients, the gas phase electron density in the anode can vary by orders of magnitude. Varying reflection of electrons by the interface also has consequences for the electron energy profile; increasing reflection may lead to increasing thermalization of electrons depending on choices about the electron energy boundary condition. This variation in anode electron density and energy as a function of the interface characteristics could also lead to significant variation in near-surface gas chemistries when such reactions are included in the model; this could very well in turn affect the reactive species impinging on the liquid surface. We draw the conclusion that in order to make more confident model predictions about plasma-liquid systems, finer scale simulations and/or new experimental techniques must be used to elucidate the near-surface gas phase electron dynamics.

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“…This is particularly true in plasma jets flowing towards a humid target. Atmospheric pressure plasma jets [1,2] are widely used in Plasma Medicine issues [3]. The gas mixture composition and the physics of the discharge strongly depend on the presence of the target, and local discharge conditions change in a sub-mm space scale.…”

Section: Introductionmentioning

confidence: 99%

Laser induced fluorescence in atmospheric pressure discharges

Dilecce

Martini

Tosi

et al. 2015

Plasma Sources Sci. Technol.

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Abstract.This paper offers an outline of Laser Induced Fluorescence (LIF) diagnostics and practical recommendations for its use in atmospheric pressure discharges. LIF principles, technical requirements and rationalization of experimental outcomes by modelling are addressed. Important issues that are particularly relevant to small scale, spatially inhomogeneous discharges, like plasma-jets, are emphasized. For the first time, all collision processes and the spatial non-homogeneity of the laser beam are together accounted for in the LIF model. Saturation characteristics are discussed and used for the assessment of model parameters. A calibration procedure is discussed and implemented. Gas temperature measurements by LIF are also addressed. The whole description of the technique is given, without loss of generality, through the example of its application to the OH radical. Notes on other diatomic radicals, CH, NO and CN, are given along the paper. Some results in a RF plasma-jet are presented as an example of application in a discharge system where all the concepts developed in the paper are applied.

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Plasmas for medicine

Cited by 749 publications

References 295 publications

Power measurement for an atmospheric pressure plasma jet at different frequencies: distribution in the core plasma and the effluent

Power measurement for an atmospheric pressure plasma jet at different frequencies: distribution in the core plasma and the effluent

Fully coupled simulation of the plasma liquid interface and interfacial coefficient effects

Laser induced fluorescence in atmospheric pressure discharges

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