Plasmacytoma Manifesting as Recurrent Cellulitis and Hematic Cyst of the Orbit

Recurrent unilateral periorbital cellulitis in a pediatric patient—An anatomic abnormality

“…These occurred in both children and adults [3]. Other reported etiologies of RPOC have included periocular malignancy (nonHodgkin's lymphoma [4], plasmacytoma [5]), and immunodeficiency/neutropenia [6]. Certainly, a broad differential diagnosis must be entertained when dealing with RPOC.…”

Orbital Plasmacytoma Mimicking an Orbital Abscess

“…4 Rare presentations of orbital plasmacytomas include mimicking a chalazion, mimicking a lacrimal gland tumor, mimicking dacryocystitis, eyelid ecchymosis, angioedema-like eyelid edema, variable ptosis, fungating eyelid lesions, isolated extraocular muscle infiltration, orbital hemorrhage, Tolosa Hunt syndrome, or orbital cellulitis. [5][6][7][8][9][10][11][12][13][14][15] Orbital exploration with biopsy or fine needle aspiration biopsy 11,16 should be performed to make an accurate diagnosis of plasmacytoma.…”

“…6 The other presented with a recurrent preseptal cellulitis with hematic cyst formation from an extramedullary plasmacytoma from the orbit and middle cranial fossa. 8 The work-up for multiple myeloma was negative and the patient was effectively treated with radiation.…”

Recurrent periorbital cellulitis in a very young child: A case report and review of literature

“…As well, some very rare conditions that should be considered include disorders that may mimic RPOC or occur as co-morbid conditions. They include malignancies, such as B-cell nonHodgkin's lymphoma [12] and plasmacytoma [13]; infections, such as orbital cysticerosis, post-operative atypical mycobacterial infection after periorbital cosmetic surgery [14] and HIV infection [15]; and hereditary disorders, such as Shwachman-Diamond syndrome [16]. Recognizing the broad differential is key to the evaluation and management of RPOC patients.…”