Plasmacytoid variant of urothelial carcinoma of the bladder manifesting as bilateral ureteral and small bowel obstruction

Abstract

Plasmacytoid urothelial carcinoma (PUC) is a rare variant of bladder cancer characterized by distinct histopathology and advanced stage at diagnosis. Multimodal treatment is usually indicated. We present a case of PUC causing bilateral ureteral obstruction with subsequent renal failure followed shortly by malignant small bowel obstruction, demonstrating the need for a high degree of clinical suspicion in diagnosis of this aggressive subtype. Moreover, the local invasiveness of the disease cannot be understated, given that it can rapidly spread with little radiologic evidence of progression until it is at an advanced stage.

Gastric Outlet Obstruction as a presentation of Metastatic Squamous Cell Carcinoma of the Bladder: A case report and review of the literature

“…There are few reports of duodenal obstruction secondary to bladder cancer and rare variants such as plasmacytoid variant [ [8] , [9] , [10] , [11] , [12] , [13] , [14] ], and a case report of small bowel obstruction [ 15 ], and few cases of large bowel and rectal obstruction secondary to invasive and metastatic disease [ 16 , 17 ]. However there are no cases of gastric outlet obstruction secondary to metastatic non-bilharzial Squamous cell carcinoma of the bladder as an initial presentation.…”

Metastatic Urothelial Cancer Presenting as Small Bowel Obstruction: A Case Report

“…Bladder cancer is the most common malignancy of the urinary tract, with urothelial cancer making up approximately 90% of all bladder cancers [5]. While urothelial cancer is known to metastasize to lymph nodes, bones, lungs, liver, and peritoneum, it is an extremely rare cause of SBO, with only a handful of cases described in the literature to date [6][7][8][9]. In this case report, we present a case of metastatic duodenal SBO secondary to metastatic urothelial carcinoma.…”