Plasmablastic extramedullary plasmacytoma

Ponniah, Irulandy; Rajan, Suhasini

doi:10.4103/0377-4929.94874

Cited by 4 publications

(6 citation statements)

References 1 publication

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“…Overall, imaging findings of PCN in the head and neck region are small, well‐defined or simple lesions 28,30,53,64,72,78,104 . Moreover, an extensive radiolucent area with an irregular and destructive pattern has been documented 22,23,25,26,29,31,35,38,42–44,60,83,92,94,105 . The most common features found in our review were an expansive mass along with osteolytic/ill‐defined appearances 23,25,26,29,31,35,38,42–44,60,83,92,94 .…”

Section: Discussionmentioning

confidence: 61%

“…The electronic searches yielded 1143 articles (PubMed: 418, Web of Science: 292, Embase: 265, and Scopus: 168) and 82 studies reporting 102 individuals were included in this systematic review 17–98 (Figure 1).…”

Section: Resultsmentioning

confidence: 99%

“…28,30,53,64,72,78,104 Moreover, an extensive radiolucent area with an irregular and destructive pattern has been documented. 22,23,25,26,29,31,35,38,[42][43][44]60,83,92,94,105 The most common features found in our review were an expansive mass along with osteolytic/ill-defined appearances. 23,25,26,29,31,35,38,[42][43][44]60,83,92,94 Tillawi et al, 93 for instance, described a case of cervical plasmacytoma as a large, irregular, expansive, infiltrating, heterogenous bone lesion that had destroyed the fourth cervical vertebral body and extended into the adjacent soft tissues.…”

Section: Demographic Data and Clinical Featuresmentioning

confidence: 99%

“…22,23,25,26,29,31,35,38,[42][43][44]60,83,92,94,105 The most common features found in our review were an expansive mass along with osteolytic/ill-defined appearances. 23,25,26,29,31,35,38,[42][43][44]60,83,92,94 Tillawi et al, 93 for instance, described a case of cervical plasmacytoma as a large, irregular, expansive, infiltrating, heterogenous bone lesion that had destroyed the fourth cervical vertebral body and extended into the adjacent soft tissues. The imaging approach varied widely across studies, ranging from radiography, ultrasound, tomography and magnetic resonance to PET-scan, but all were used to guide further investigation.…”

Section: Demographic Data and Clinical Featuresmentioning

confidence: 99%

“…A recent systematic review identified concordance rates higher than 64% for the smear and 77% for the cell‐block technique regarding diagnostic capability for the evaluation of intraosseous jaw lesions, including malignant lesions 16 . Despite several published reports on the cytopathological diagnosis of PCN, either in isolated manifestations (extramedullary or solitary bone plasmacytoma) or as a consequence of PCM, 17–98 there is a lack of compiled information investigating the agreement of cytopathological and histopathological findings, along with others ancillary cytological methods such as smears and cell blocks. In fact, FNAC represents a faster, cheaper and more diversified noninvasive diagnostic approach.…”

Section: Introductionmentioning

confidence: 99%

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Fine‐needle aspiration cytology for the diagnosis of plasma cell neoplasms in the head and neck region: A systematic analysis of the literature

Felix

SENA

Arruda

et al. 2022

Diagnostic Cytopathology

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Background Cytopathologic analysis is feasible and provides detailed morphological characterisation of head and neck lesions. Aims To integrate the available data published on fine‐needle aspiration cytology (FNAC) used for the diagnosis of plasma cell neoplasms (PCN) of the head and neck region. Materials and Methods Searches on PubMed, Web of Science, Embase, and Scopus were performed to compile data from case reports/case series published in English. The Joanna Briggs Institute tool was used for the critical appraisal of studies. Results A total of 82 studies comprising 102 patients were included in this review. There was a predilection for men (68.6%) (male/female ratio: 2.1:1). Individuals in their 50s (29.4%), 60s (22.5%), and 70s (22.5%) were more often affected. The thyroid gland (26.2%) was the main anatomical location, followed by scalp (15.5%), neck/cervical region (15.5%), jaws (13.6%), and major salivary glands (13.6%). For FNAC analysis, a smear was employed in 41 (40.6%) cases and a cell block was used in four (3.9%). In 56 (55.4%) reports, no cytological methods were available. Morphologically, 34 (56.7%) cases had a diagnosis of PCN with agreement between cytopathology and histopathology. The rate of wrong diagnoses when using cytology was 27.5%. Immunophenotyping was performed in 49 (48%) of the cases. The 69‐month disease‐free survival rate was 60.2%, while the 27‐month overall survival rate was 64.1%. Conclusion This study reinforces that FNAC can be an ancillary tool in the first step towards the diagnosis of PCN of the head and neck region, especially when applying a cell block for cytological analysis.

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Section: Discussionmentioning

confidence: 61%

Section: Resultsmentioning

confidence: 99%

Section: Demographic Data and Clinical Featuresmentioning

confidence: 99%

Section: Demographic Data and Clinical Featuresmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Fine‐needle aspiration cytology for the diagnosis of plasma cell neoplasms in the head and neck region: A systematic analysis of the literature

Felix

SENA

Arruda

et al. 2022

Diagnostic Cytopathology

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An elderly man with a gingival mass that spontaneously regressed

González-Pérez

Martín

2016

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

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Recent Advances in Aggressive Large B-cell Lymphomas: A Comprehensive Review

Korkolopoulou¹,

Vassilakopoulos²,

Milionis³

et al. 2016

Advances in Anatomic Pathology

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Diffuse large B-cell lymphoma (DLBCL) is an aggressive disease with considerable heterogeneity reflected in the 2008 World Health Organization classification. In recent years, genome-wide assessment of genetic and epigenetic alterations has shed light upon distinct molecular subsets linked to dysregulation of specific genes or pathways. Besides fostering our knowledge regarding the molecular complexity of DLBCL types, these studies have unraveled previously unappreciated genetic lesions, which may be exploited for prognostic and therapeutic purposes. Following the last World Health Organization classification, we have witnessed the emergence of new variants of specific DLBCL entities, such as CD30 DLBCL, human immunodeficiency virus-related and age-related variants of plasmablastic lymphoma, and EBV DLBCL arising in young patients. In this review, we will present an update on the clinical, pathologic, and molecular features of DLBCL incorporating recently gained information with respect to their pathobiology and prognosis. We will emphasize the distinctive features of newly described or emerging variants and highlight advances in our understanding of entities presenting a diagnostic challenge, such as T-cell/histiocyte-rich large B-cell lmphoma and unclassifiable large B-cell lymphomas. Furthermore, we will discuss recent advances in the genomic characterization of DLBCL, as they may relate to prognostication and tailored therapeutic intervention. The information presented in this review derives from English language publications appearing in PubMed throughout December 2015. For a complete outline of this paper, please visit: http://links.lww.com/PAP/A12.

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Plasmablastic extramedullary plasmacytoma

Cited by 4 publications

References 1 publication

Fine‐needle aspiration cytology for the diagnosis of plasma cell neoplasms in the head and neck region: A systematic analysis of the literature

Fine‐needle aspiration cytology for the diagnosis of plasma cell neoplasms in the head and neck region: A systematic analysis of the literature

An elderly man with a gingival mass that spontaneously regressed

Recent Advances in Aggressive Large B-cell Lymphomas: A Comprehensive Review

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