Plasma surface modification of polymers for biomedical use

Oehr, Christian

doi:10.1016/s0168-583x(03)00650-5

Cited by 195 publications

(139 citation statements)

References 6 publications

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“…Plasma-and chemical-based etching occurs when a surface is exposed to etching gas, which is often a type of plasma, and the top layer of the surface is changed through chain scission processes where old bonds are broken and new ones formed; more simply, etching degrades the polymer surface [24,47,48]. This process also modifies the surface topography and affects surface wettability, potentially driving the surface to become more biocompatible [47,48].…”

Section: Surface Rougheningmentioning

confidence: 99%

Section: Surface Rougheningmentioning

confidence: 99%

“…This process also modifies the surface topography and affects surface wettability, potentially driving the surface to become more biocompatible [47,48]. Etching can also be performed prior to coating a material, to ensure that the coating adheres [48]. Treatment with particular acids, which has an "etching effect", may also encourage attachment and migration of endothelial cells, especially in polymeric hydrogels [49].…”

Section: Surface Rougheningmentioning

confidence: 99%

“…Low pressure plasma treatments that use electrons, ions, radicals, metastables or ultraviolet rays (UV) radiation elicit reactions at the surface of polymers [48]. For plasma-based treatments, ammonia plasma treatment may encourage cell attachment more through the interaction of acidic groups on the plasma membrane surface and amine/amide groups on the surface of the polymer, which play an important role in endothelial cell adhesion and growth [21,80].…”

Section: Chemical Modification Of the Surfacementioning

confidence: 99%

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A Survey of Surface Modification Techniques for Next-Generation Shape Memory Polymer Stent Devices

Govindarajan

Shandas

2014

Polymers

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Abstract:The search for a single material with ideal surface properties and necessary mechanical properties is on-going, especially with regard to cardiovascular stent materials. Since the majority of stent problems arise from surface issues rather than bulk material deficiencies, surface optimization of a material that already contains the necessary bulk properties is an active area of research. Polymers can be surface-modified using a variety of methods to increase hemocompatibilty by reducing either late-stage restenosis or acute thrombogenicity, or both. These modification methods can be extended to shape memory polymers (SMPs), in an effort to make these materials more surface compatible, based on the application. This review focuses on the role of surface modification of materials, mainly polymers, to improve the hemocompatibility of stent materials; additional discussion of other materials commonly used in stents is also provided. Although shape memory polymers are not yet extensively used for stents, they offer numerous benefits that may make them good candidates for next-generation stents. Surface modification techniques discussed here include roughening, patterning, chemical modification, and surface modification for biomolecule and drug delivery.

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Section: Surface Rougheningmentioning

confidence: 99%

Section: Surface Rougheningmentioning

confidence: 99%

Section: Surface Rougheningmentioning

confidence: 99%

Section: Chemical Modification Of the Surfacementioning

confidence: 99%

See 2 more Smart Citations

A Survey of Surface Modification Techniques for Next-Generation Shape Memory Polymer Stent Devices

Govindarajan

Shandas

2014

Polymers

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“…For these reasons, the use of plasma treatment seems to benefit both of the interface resistance [18,19] and the interface biocompatibility [20]. It was also used in polymeric materials to improve the efficacy of voice prosthesis [22] or to fulfill the requirements medical in medical applications [23].…”

Section: Introductionmentioning

confidence: 99%