Plasma Surface Modification of Biomedical Polymers: Influence on Cell-Material Interaction

Jacobs, Tinneke; Morent, Rino; Geyter, Nathalie De; Dubruel, Peter; Leys, Christophe

doi:10.1007/s11090-012-9394-8

Cited by 212 publications

(149 citation statements)

References 156 publications

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“…Argon plasma improves the surface hydrophilicity (through the formation of oxygen surface functionalities upon the exposure of the reactive polymer surface to the ambient conditions) without affecting the bulk characteristics [4,13,14]. Due to the versatility of this technology, it might be useful in many different applications [15,16].…”

Section: Introductionmentioning

confidence: 99%

Enhanced adherence of mouse fibroblast and vascular cells to plasma modified polyethylene

Řezníčková

Novotná

Kolská

et al. 2015

Materials Science and Engineering: C

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Section: Introductionmentioning

confidence: 99%

Enhanced adherence of mouse fibroblast and vascular cells to plasma modified polyethylene

Řezníčková

Novotná

Kolská

et al. 2015

Materials Science and Engineering: C

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“…Moreover, different reactive species can be formed in the plasma depending on the used dilution gas (e.g., helium, argon, air or nitrogen), which also affects the characteristics of the coating [25,[36][37][38].…”

Section: Plasma Polymerizationmentioning

confidence: 99%

Plasma Polymerization for Tissue Engineering Purposes

Aziz¹,

Ghobeira²,

Morent³

2018

Recent Research in Polymerization

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The ability of non-equilibrium plasmas to modify surfaces has been known for many years. And a promising way to perform surface modifications without altering the bulk properties is plasma polymerization since this technique is versatile and can be applied to a wide range of materials. Plasma polymer films usually show good biocompatibility when compared to classical biomaterials. The possible biomedical use of plasma polymers motivates the study of their behavior during storage and in aqueous environment. Therefore, it is of major importance to understand the change of properties of these plasma polymers over time and when in contact with certain fluids. Recently, plasma polymer gradients (surfaces that display a change in at least one physicochemical property over distance) have attracted significant attention from the biomedical filed where the interaction of cells with a material surface is of major interest. This chapter discusses biomaterial functionalization via plasma polymerization focusing on their use in the biomedical field as well as their aging and stability behaviors. Plasma polymer gradients as valuable tools to investigate cell-surface interactions will also be reviewed.

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“…Their main disadvantage is their lack of proper surface properties that stimulate the adhesion and proliferation of cells and differentiate them into the right type of tissue [44]. Numerous wet-chemical techniques have been developed and applied, but most of them are either too aggressive, (partially) destroying the delicate structures, showing low treatment efficiency, time-consuming, or waste generating...…”

Section: The Added Value Of Non-thermal Plasma Technologymentioning

confidence: 99%

Plasma Science and Technology - Progress in Physical States and Chemical Reactions

Mieno¹

2016

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Non-thermal plasma technology is one of those techniques that suffer relatively little from diffusion limits, slow kinetics, and complex geometries compared to more traditional liquid-based chemical surface modification techniques. Combined with a lack of solvents, preservation of the bulk properties, and fast treatment times; it is a well-liked technique for the treatment of materials for biomedical applications. In this book chapter, a review will be given on what the scientific community determined to be essential to obtain appropriate scaffolds for tissue engineering and how plasma scientists have used non-thermal plasma technology to accomplish this. A distinction will be made depending on the scaffold fabrication technique, as each technique has its own set of specific problems that need to be tackled. Fabrication techniques will include traditional fabrication methods, rapid prototyping, and electrospinning. As for the different plasma techniques, both plasma activation and grafting/polymerization will be included in the review and linked to the in-vitro/in-vivo response to these treatments. The literature review itself is preceded by a more general overview on cell communication, giving useful insights on how surface modification strategies should be developed.

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Plasma Surface Modification of Biomedical Polymers: Influence on Cell-Material Interaction

Cited by 212 publications

References 156 publications

Enhanced adherence of mouse fibroblast and vascular cells to plasma modified polyethylene

Enhanced adherence of mouse fibroblast and vascular cells to plasma modified polyethylene

Plasma Polymerization for Tissue Engineering Purposes

Plasma Science and Technology - Progress in Physical States and Chemical Reactions

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