Plasma-sprayed titanium coating to polyetheretherketone improves the bone-implant interface

Walsh, William R.; Bertollo, Nicky; Christou, Chris; Schaffner, Dominik; Mobbs, Ralph J.

doi:10.1016/j.spinee.2014.12.018

Cited by 161 publications

(128 citation statements)

References 40 publications

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“…The studies are numbered in a descending order corresponding to their respective levels of evidence (Table 2) Eur Spine J further close the gap [12]. However, the PEEK implant interface often exhibits a ''halo'' effect, i.e., a peri-prosthetic lucency around the implant radiographically, which is associated with unsuccessful fusion [13,25].…”

Section: Materials Selectionmentioning

confidence: 99%

“…Support for the clinical use of Ti coatings to PEEK has been reported in the literature. In vitro cell culture studies demonstrate the benefit of a titanium interface for PEEK for cellular attachment and osteoblastic phenotype expression [7,11,12] as well as bone on-growth and an increase in shear strength with a titanium coating in an idealized model [13].…”

Section: Introductionmentioning

confidence: 99%

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Radiological and clinical outcomes of novel Ti/PEEK combined spinal fusion cages: a systematic review and preclinical evaluation

et al. 2015

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Clinical studies at this early stage demonstrate that Ti/PEEK implants are safe and efficacious, exhibiting similar fusion rates and clinical outcomes compared to the current standard PEEK. There is clinical evidence substantiating the improved radiographic fusion of Ti/PEEK, albeit the differences were not significant. This field is promising, gaining substantial popularity, and further clinical trials are needed in the future to establish Ti/PEEK cages as a mainstay of clinical practice.

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Section: Materials Selectionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Radiological and clinical outcomes of novel Ti/PEEK combined spinal fusion cages: a systematic review and preclinical evaluation

et al. 2015

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“…It was shown that PEEK implants coated by a Materiali in tehnologije / Materials and technology 52 (2018) 1, 99-102 thin layer of titanium improves bioactivity of material and consequently enhance osseointegration. 18 Recently, biomechanical and histologic analyses were performed in an ovine lumbar interbody fusion model. Ti-Peek construct demonstrated significant increase in bone on-growth.…”

Section: Titanium-polyetheretherketone Composite Cagesmentioning

confidence: 99%

Towards the optimum spinal fusion device

Gorenšek¹,

Jenko²,

Kocjančič³

et al. 2018

Mater. Tehnol.

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Spinal interbody fusion (spondylodesis) remains a gold standard for the treatment of instability, deformity and degenerative disease of the spine. Over the past 40 years surgical techniques and implant-device (cage) technology for spinal fusion have changed significantly. Design and materials have evolved with one common goal, to develop suitable implants that would address all three major issues of the procedure: stability, restoration of lordosis and osteointegration. Historically, two main materials have been utilized in the creation of cages: titanium (Ti) and polyetheretherketone (PEEK). The focus of spinal surgeons is constantly shifting from one material to another, because of the aggressive, commercial drive from the industry. The choice of optimal spinal interbody fusion device was always a matter of controversy. Therefore, this article aims to provide an overview of the different materials and designs from the biomechanical and also clinical aspect. A systematic review of the literature was made. The inadequate available clinical trials and lack of comparisons between different models have prevented definitive conclusions; therefore, further prospective randomized studies are necessary in the future to define one cage as a mainstay of clinical practice. Keywords: spondylodesis, cage, titanium, polyetheretherketone Zatrditev hrbteni~nega segmenta (spondilodeza) predstavlja zlati standard zdravljenja nestabilnosti, deformacij in degenerativnih bolezni hrbtenice. V zadnjih 40 letih so se kirur{ka tehnika in umetni medvreten~ni vsadki (kletke) ob~utno spremenili. Oblika in materiali so se razvijali z enim skupnim ciljem, to je odkriti vsadek, ki bi omogo~al stabilnost hrbteni~nega segmenta, vzdr`evanje lordoze ter osteointegracijo. Zgodovinsko gledano sta bila dva najpogosteje uporabljena materiala titan in polietereterketon. Dandanes med hrbteni~nimi kirurgi ostaja nesoglasje glede optimalne izbire umetnega medvreten~nega vsadka. Namen tega~lanka je predstaviti prednosti in slabosti najpogosteje uporabljenih materialov. Na podlagi aktualne strokovne literature je bila opravljena primerjava biomehanskih in klini~nih rezultatov razli~nih vsadkov. Glede na pomanjkljivost naklju~nih prospektivnih multicentri~nih {tudij ostaja izbira optimalnega umetnega hrbteni~nega vsadka {e naprej problemati~na.

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“…Consequently, various surface modification approaches have been developed to promote the hydrophilic and biological characteristics of PEEK, such as using plasma treatment to change the surface chemistry [29], using chemical treatment to graft functional groups [30], and using laser treatment to roughen the surface [31]. Moreover, adding a functional coating to PEEK to create a bioactive surface is a more effective method for enhancing osseointegration performance [32][33][34][35][36][37][38]. Functional coating materials include HA [32], titanium [33,34], TiO 2 [35][36][37], and diamond-like carbon [38].…”

Section: Introductionmentioning

confidence: 99%

“…Moreover, adding a functional coating to PEEK to create a bioactive surface is a more effective method for enhancing osseointegration performance [32][33][34][35][36][37][38]. Functional coating materials include HA [32], titanium [33,34], TiO 2 [35][36][37], and diamond-like carbon [38]. To date, by taking the advantage of good biocompatibility of titanium with human body, very thick titanium produced over PEEK surface via vacuum plasma spray for spinal implant has been clinically available.…”

Section: Introductionmentioning

confidence: 99%

Anticorrosive, Antimicrobial, and Bioactive Titanium Dioxide Coating for Surface‐modified Purpose on Biomedical Material

Tsou¹,

Hsieh²

2017

Application of Titanium Dioxide

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A multifunctional titanium dioxide (TiO 2 ) coating was used to provide anticorrosive, antimicrobial, and bioactive properties for the surface modification of biomedical materials because TiO 2 has a stable bonding structure, photocatalytic characteristics, and negatively charged surfaces in nature. For successful deposition, an arc ion plating technique was adopted to deposit the TiO 2 coating. The antimicrobial activity values of anataseTiO 2 -coated stainless steel specimens against Staphylococcus aureus and Escherichia coli were 3.0 and 2.5, respectively, which are far beyond the value designated in JIS Z2801:2000 industrial standard. TiO 2 coatings on stainless steel also generate an increased (i.e., less negative) corrosion potential and decreased corrosion current in a sodium chloride solution, showing a reduced tendency and rate of substrate dissolution as well as a reduced coating of species into the electrolyte. In addition, TiO 2 coatings, especially with rutile phase, satisfied the requirements for activating the biological property of a polymeric polyetheretherketone surface. Therefore, TiO 2 is a promising surface modification for the biomedical materials used in surgical instruments and implants.

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Plasma-sprayed titanium coating to polyetheretherketone improves the bone-implant interface

Cited by 161 publications

References 40 publications

Radiological and clinical outcomes of novel Ti/PEEK combined spinal fusion cages: a systematic review and preclinical evaluation

Radiological and clinical outcomes of novel Ti/PEEK combined spinal fusion cages: a systematic review and preclinical evaluation

Towards the optimum spinal fusion device

Anticorrosive, Antimicrobial, and Bioactive Titanium Dioxide Coating for Surface‐modified Purpose on Biomedical Material

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