Plasma Progesterone During Pregnancy in the Mouse<sup>1</sup>

Murr, Sandra M.; Stabenfeldt, G. H.; Bradford, G. E.; Geschwind, Irving I.

doi:10.1210/endo-94-4-1209

Cited by 122 publications

(70 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The results from this investigation are in better agreement with the findings of McCormack and Greenwald (1974), who showed very similar levels on the same days, than with Murr et al (1974b) who demonstrated levels 10 times these on days 1 and 2 and levels twice those shown on day 4. The low levels of progesterone found in the present study on days I and 2 also agree with the indirect biological evidence of Finn and Martin (1969) that progesterone secretion does not begin until around 48 h p.c.…”

Section: Discussionsupporting

confidence: 89%

“…It also fits the histological evidence of Choudary and Greenwald (1969) showing that development of luteal cells starts on day 2 but fully developed luteal cells are not recognizable until day 3. Neither McCormack and Greenwald (1974) nor Murr et al (1974b) showed the sharp rise and fall of progesterone early on day 4; this may be because they took samples only once a day or it may reflect differences in the strains of mice used in the investigations.…”

Section: Discussionmentioning

confidence: 94%

“…Bindon interpreted this drop in FSH content as a release of the hormone. Murr et al (1974b) and McCormack and Greenwald (1974) made daily measurements of plasma progesterone levels during pregnancy, and the latter authors also made daily measurements of plasma oestradiol-17p. These results indicate that progesterone rises prior to implantation and that oestradiol, which is high on day 1, drops sharply on day 2 with a significant rise on day 4.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Plasma Progesterone, FSH and LH Levels Associated with Implantation in the Mouse

Gidley-Baird¹

1977

Aust. Jnl. Of Bio. Sci.

View full text Add to dashboard Cite

Aust. J. Bioi. Sci., 1977, 30, 289-96 Measurement of plasma progesterone, LH and FSH were made every 6 h during the first 6 days of pregnancy in the mouse. Plasma progesterone and LH were low on day 1, minimum values being recorded at 24 h post coitus. Concentrations of both these hormones started rising during the second half of day 2 with the rise continuing during day 3 to a progesterone peak of 25 ng/ml early on day 4 and an LH peak of 37 ng/mllate on day 4. Levels of progesterone fell during day 4 and LH during day 5 to approximately half their respective peak values and then remained relatively constant over the remainder of the measurement period. Levels of FSH, which were high early on day 1 (180 ng/ml), fell sharply by midday with a small rise late in the day followed by a decline during day 2 to a minimum level of 20 ng/ml at 48 h post coitus. Early on day 3 FSH values rose to 120 ng/ml then fell to 50-60 ng/ml during the next 6 h and remained relatively stable at this level during days 4 and 5. It is suggested that LH is concerned with progesterone production and maintenance of the corpus luteum whilst FSH is concerned with the production of oestrogen required for implantation in this species.

show abstract

Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 94%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Plasma Progesterone, FSH and LH Levels Associated with Implantation in the Mouse

Gidley-Baird¹

1977

Aust. Jnl. Of Bio. Sci.

View full text Add to dashboard Cite

show abstract

“…134 In a seemingly conflicting finding, however, progesterone was found to stimulate the synthesis of the lysosomal proteinase cathepsin-D in the uterine epithelial cell layer of ovariectomized mice. 135 In vivo, circulating concentrations of progesterone are maintained at high levels during the implantation period in pregnant mice 136 and rats. 137 Levels of progesterone receptor mRNA and protein expression remain also high in uterine tissues, 112 indicating that if ovarian hormones are involved in the regulation of uterine cell death, they must operate at a more subtil level.…”

Section: Mechanisms Of Cell Death In the Uterusmentioning

confidence: 99%

Apoptosis at the time of embryo implantation in mouse and rat

1999

View full text Add to dashboard Cite

The aim of this review is to summarize the information currently available regarding the occurrence of apoptosis in the developing embryo and in the receptive uterus during the peri-implantation period of gestation. Cell death is detected in the inner cell mass of late pre-implantation embryos as the result of an eliminative process that helps trim the embryonic cell lineages of surplus or dysfunctional stem cells. Cell death is also detected in the epiblastic core of early postimplantation embryos, where the process is implicated in the formation of the pro-amniotic cavity. On the maternal side, uterine epithelial cells situated around the attachment site undergo cell death during the initial phase of implantation in order to facilitate embryo anchorage and access to maternal blood supply. Uterine stromal cells closest to the implantation chamber first transform into decidual cells and then commit suicide to make room for the rapidly growing embryo. Although apoptosis is well recognized as a crucial determinant of successful peri-implantation development, our understanding of the cellular and molecular mechanisms regulating this process clearly lags behind the comprehension of cell death control in other systems.

show abstract

“…Plasma progesterone levels in mice normally are high throughout most of the gestation period and decline just before parturition (Murr et al, 1974 (Koller, 1952(Koller, , 1956Lisk et al, 1969). It is probable that progester¬ one must synergize with small amounts of oestrogen in order to produce maximum nest-building because mice with ovaries exhibit greater amounts of nest-building in response to progesterone administration than do mice without ovaries (Lisk et al, 1969), and large amounts of oestrogen can block progesterone-induced nest-building (Lisk, 1971).…”

mentioning

confidence: 99%

Maternal Nest-Building Performance and Fetal Number in Rockland-Swiss Albino Mice

Gandelman¹

1975

Reproduction

View full text Add to dashboard Cite

(Koller, 1952(Koller, , 1956 (Koller, 1952(Koller, , 1956Lisk et al., 1969). It is probable that progester¬ one must synergize with small amounts of oestrogen in order to produce maximum nest-building because mice with ovaries exhibit greater amounts of nest-building in response to progesterone administration than do mice without ovaries (Lisk et al., 1969), and large amounts of oestrogen can block progesterone-induced nest-building (Lisk, 1971). Gonadectomized males are unresponsive to progesterone and oestrogen treatment unless gonadectomy is performed at birth (Lisk et al., 1973). Gonadectomized females injected with testosterone propionate at birth fail to show nest-building in response to progesterone and oestrogen treatment. These findings, and the fact that the simultaneous administration of oestrogen and testosterone propionate to intact females does not induce nest-building, indicate that nest-building is sexually dimorphic as a result of the presence of androgen (Gandelman, 1973).While observing maternal nest-building of mice, it became apparent that large differences existed between animals with respect to nest-building per¬ ii 551

show abstract

Plasma Progesterone During Pregnancy in the Mouse¹

Cited by 122 publications

References 0 publications

Plasma Progesterone, FSH and LH Levels Associated with Implantation in the Mouse

Plasma Progesterone, FSH and LH Levels Associated with Implantation in the Mouse

Apoptosis at the time of embryo implantation in mouse and rat

Maternal Nest-Building Performance and Fetal Number in Rockland-Swiss Albino Mice

Contact Info

Product

Resources

About

Plasma Progesterone During Pregnancy in the Mouse1

Cited by 122 publications

References 0 publications

Plasma Progesterone, FSH and LH Levels Associated with Implantation in the Mouse

Plasma Progesterone, FSH and LH Levels Associated with Implantation in the Mouse

Apoptosis at the time of embryo implantation in mouse and rat

Maternal Nest-Building Performance and Fetal Number in Rockland-Swiss Albino Mice

Contact Info

Product

Resources

About

Plasma Progesterone During Pregnancy in the Mouse¹