Plasma progesterone concentrations in heifers and cows treated with a new intravaginal device

Kl, Macmillan; Taufa, V.K.; Barnes, Debra A.; Day, A.M.

doi:10.1016/0378-4320(91)90063-6

Cited by 78 publications

(41 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Otherwise, it is in disagreement with others who reported maximum progesterone concentration after few minutes, hours or during the day CIDR insertion (Rathbone et al, 2002;Zuluaga and Williams, 2008;Long et al, 2009;Carvalho et al, 2014). The stage of cycle at which CIDR was inserted found to influence the changes in the progesterone concentration (Macmillan et al, 1991) may be due to variable progesterone absorption ability of the vaginal membrane at different stage of estrus. Slow increase in the serum progesterone level after CIDR may be due to insertion of CIDR at day of estrus.…”

Section: Advances In Animal and Veterinary Sciencescontrasting

confidence: 52%

Efficiency of Previously used CIDR Stored for a Prolonged Period

Abdallah¹,

Elrahim²

2014

Adv. Anim. Vet. Sci.

View full text Add to dashboard Cite

| This study investigated the efficiency of the previously used controlled internal drug release (CIDR) stored for 30 days before reusing. In the first experiment, twenty seven Holstein cows at the day of estrus (day 0) received either no treatment (control), new or reused CIDR and blood samples were collected at day 0, 1, 3 and 7. At day 1 and 3, serum progesterone concentration in cows received new CIDR (1.417 and 1.616 ng/ml) was significantly higher than in cows received a reused one (0.545 and 0.954 ng/ml) which in turn was higher than the control group. In the second experiment, estrous cycle was synchronized using Ovsynch, New-CIDRsynch or Reused-CIDRsynch. Cows in Ovsynch (n=119) received GnRH on day 0 then PGF2α on day 7. Fifty six hours after the PGF2α cows received another dose from GnRH and inseminated 18 h latter. Cows in new-CIDRsynch (n=870) and reused-CIDRsynch (n=220) were treated in the same way with exception of inserting a new or reused CIDR between day 0 and day 7. Non returned cows were examined for pregnancy diagnosis at 30 and 70 days post-insemination. Pregnancy-30 and 70 rates after New-CIDRsynch (36.1% and 30.5%) and Reused-CIDRsynch (36.4% and 31.8%) tended to be higher than after Ovsynch (27.7% and 25.2%) (P= 0.07: 0.08). In conclusion, the previously used CIDR -stored for 30 days-have residual progesterone and incorporating new or reused CIDR into Ovsynch improved the efficiency of the protocol in a similar way.

show abstract

Section: Advances In Animal and Veterinary Sciencescontrasting

confidence: 52%

Efficiency of Previously used CIDR Stored for a Prolonged Period

Abdallah¹,

Elrahim²

2014

Adv. Anim. Vet. Sci.

View full text Add to dashboard Cite

show abstract

“…However, if its reutilization efficiency could be proved, it would be a valuable management tool for farmers. For cattle, it is well known that these devices release progesterone (P4) for at least 15 days (MacMillan et al, 1991) and if this could be reproduced for ewes, when working with shortterm protocols, it would mean that they might potentially be used up to three times.…”

Section: Introductionmentioning

confidence: 99%

Reproductive parameters of Santa Inês ewes submitted to short-term treatment with re-used progesterone devices

Pinna

Brandão

Cavalcanti

et al. 2012

Arq. Bras. Med. Vet. Zootec.

View full text Add to dashboard Cite

The aim of this study was to verify the efficacy of reusing intravaginal progesterone (P4) devices on the reproductive parameters in Santa Inês ewes. Females received intravaginal P4 devices for their first, second or third use for five days plus 300 IU eCG IM and 5mg dinoprost laterovulvar 24h before device removal. Blood was collected at different moments. Transrectal ultrasonography was performed from device removal to ovulation. Part of the ewes were submitted to artificial insemination by laparoscopy (IAL -n=55) with fresh semen, whereas the rest were bred by fertile rams (n=41). On the initial 18 h, ewes that received devices for the first time showed higher P4 concentrations (5.1±1.8 vs 3.5±1.4 vs 2.4±1.1 -P<0.05). However, after the first 48h no difference was observed among all treatments and P4 supraluteal concentrations were detected in all ewes upon device removal. Estrous response, interval from device removal to estrus, rate of ovulating animals, number of ovulations, time from device removal to ovulation and average conception rates after IAL or natural mating were similar among all 3 groups. Intravaginal progesterone devices can be used up to three times without altering reproductive parameters in Santa Inês ewes.Keywords: sheep, artificial insemination, CIDR, intravaginal progesterone insert, ovulation Palavras-chave: ovino, inseminação artificial, CIDR, dispositivo intravaginal de progesterona, ovulação RESUMO Avaliou-se a eficácia da reutilização de dispositivos intravaginais de progesterona (P4) sobre características reprodutivas em ovelhas Santa Inês. As fêmeas receberam dispositivos intravaginais contendo P4 para o seu primeiro, segundo ou terceiro uso por cinco dias, associado a 300 UI eCG IM e 5mg dinoprost laterovulvar 24h antes da remoção dos dispositivos. Ultrassonografia transretal foi realizada da remoção dos dispositivos até a ovulação. Parte das ovelhas foi submetida à inseminação artificial laparoscópica (IAL-n=55) com sêmen a fresco, enquanto outra parte foi acasalada por machos férteis (n=41). Nas 18 h iniciais, as ovelhas que receberam dispositivos pela primeira vez

show abstract

“…The CIDR device was first recommended to be used for 12 days in New Zealand in 1987 (7) but later on variable intervals were reported, e.g., 5 (10), 7 (8), 9 (11), 12 (12), and 14 (13) days. Although using P 4 for longer durations produces excellent synchronization results, poor fertility linked to the maturation of stale follicles remains an obstacle.…”

Section: Introductionmentioning

confidence: 99%

Efficacy of repeatedly used CIDR device in cattle reproduction: a metaanalysisreview of progesterone concentration and conception rate

Chacher¹,

Çolak²,

Hayırlı³

2017

Turk J Vet Anim Sci

View full text Add to dashboard Cite

In order to reduce estrus synchronization cost, utilization of residual progesterone (P 4 ) in the used controlled internal drug release (CIDR) device upon sanitization can be possible. Two datasets were compiled from 8 and 7 research articles involving 3434 (2653 heifers + 771 lactating cows + 10 ovariectomized cows) and 7301 cattle (3879 heifers + 3422 lactating cows) to evaluate blood P 4 concentration and conception rate, respectively, in response to repeatedly used CIDR devices after sanitization via autoclaving and disinfection. As the number of CIDR usages increased, blood P 4 concentration decreased linearly (y = -0.484X + 3.135, R 2 = 0.99, P < 0.001). Blood P4 concentration (1.52 vs. 2.20 ng/mL; P < 0.002) and conception rate (40.76 vs. 32.96%, P < 0.05) for lactating cows were lower than those for heifers. The sanitization method did not affect blood P4 concentration, but reused CIDR device subjected to disinfection was associated with reduced conception rate. In summary, depending upon the initial P4 load (1.38-1.90 g), the CIDR device could be used twice in lactating cows and four times in heifers after autoclaving to achieve target blood P4 concentrations.

show abstract

Plasma progesterone concentrations in heifers and cows treated with a new intravaginal device

Cited by 78 publications

References 20 publications

Efficiency of Previously used CIDR Stored for a Prolonged Period

Efficiency of Previously used CIDR Stored for a Prolonged Period

Reproductive parameters of Santa Inês ewes submitted to short-term treatment with re-used progesterone devices

Efficacy of repeatedly used CIDR device in cattle reproduction: a metaanalysisreview of progesterone concentration and conception rate

Contact Info

Product

Resources

About