Plasma microRNA levels in childhood IgA vasculitis

Role of microRNAs in Immune Regulation with Translational and Clinical Applications

“…In vasculitic skin lesions of adult patients with IgA vasculitis, altered levels of let-7b, miR-148b-3p, miR-155-5p and miR-223-3p were found, among which the expression of miR-223-3p correlated with the severity of purpuras [155]. On the other hand, up-regulation of plasma miR-33 and miR-34 has been confirmed in active periods of childhood IgA vasculitis, as compared to the inactive periods and control groups [151]. A high expression level of circulating miR-24-3p was identified as a potential diagnostic biomarker of Kawasaki disease (KD) [150], whereas evaluation of miR-133a expression can support the distinction between acute and convalescent KD patients [152].…”

“…miR-17-92 (rs4284505) [113], miR-146a [114], miR-365a-3p [115], miR-4689 [116] miR-21 [117], miR-124-3p, miR-146, miR-320b, miR-377-3p [118,119] miR-181a, miR-223 [120], miR-485-5p [121] miR-7 [122], miR-30a [123], miR-181d-5p [124], miR-590-3p [125] Antiphospholipid syndrome miR-326, miR-483-3p [126] miR-19b-3p, miR-20a-5p [127] miR-146a-5p [128] Systemic sclerosis, scleroderma miR-21 [129], miR-126 [130], miR-155-5p [131] miR-21 [132], miR-27a [133], miR-29a, miR-138 [134] miR-21-5p, miR-29a-3p, miR-143, miR-155 [135], miR-181b-5p, miR-210-3p, miR-223-3p [136] miR-27a [137], miR-214 [138] Sjögren's syndrome miR-181d-5p [139], miR-223-3p [140] miR-30 [141], miR-181b-5p, miR-322-5p, miR-424-5p, miR-503-5p [142], miR-513c-3p [143], miR-1290, let-7b-5p [144] miR-92a [145] miR-16, miR-125b [146], miR-142, miR-223 [147], let-7 [148] Autoimmune vasculitis miR-424-5p [149] miR-24-3p [150], miR-30a-5p, miR-33, miR-34 [151], miR-99a-5p, miR-106b-5p, miR-133a [152], miR-146a-5p [149], miR-148b-3p, miR-155-5p, miR-182-5p…”