Lipid Metabolism in Mammals 1977
DOI: 10.1007/978-1-4684-2832-2_6
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Plasma Lipoproteins: Structure and Metabolism

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Cited by 12 publications
(8 citation statements)
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“…1, gel D). One of these, which was not always present, had a mobility 1 corresponding to that of the smaller species (apparent Mr 264,000) of apo B seen in chylomicrons; however, its amino acid composition showed it was not the same protein (see below). After separation by preparative gel electrophoresis, all these components of LDL apo B retained their respective electrophoretic mobilities (Fig.…”
Section: Resultsmentioning
confidence: 98%
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“…1, gel D). One of these, which was not always present, had a mobility 1 corresponding to that of the smaller species (apparent Mr 264,000) of apo B seen in chylomicrons; however, its amino acid composition showed it was not the same protein (see below). After separation by preparative gel electrophoresis, all these components of LDL apo B retained their respective electrophoretic mobilities (Fig.…”
Section: Resultsmentioning
confidence: 98%
“…The lipoproteins of human serum contain at least 12 species of proteins' (apolipoproteins) (1). The most abundant of these, apolipoprotein B (apo B) shares with another species, apolipoprotein E, the ability to interact with high-affinity receptors on cell membranes (2).…”
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“…The bulk of the cholesterol resides in an apolar core in which each sterol molecule is esterified with a long-chain fatty acid. This core of cholesteryl esters is surrounded by a polar coat that contains phospholipid, small amounts of unesterified cholesterol, and a protein called apoprotein B (3). In synthesizing their membranes, cells require unesterified cholesterol.…”
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confidence: 99%
“…the cow (Bos sp.) and the pig (Sus domesticusl (Osborne and Brewer, 1977 ;Kane, 1977 ;Smith, Pownall and Gotto, 1978 ;Alaupovic, 1980 ;Kane, 1983 (Puppione et al, 1982a ;1982b ;Puppione, 1983) (Puppione et al, 1982a Karlsson (1982) have shown that the major lipoprotein in fetal pig serum, at least until day 90 of gestation, is an LDL-like particle, as judged by its electrophoretic mobility and by immunoassay using an antiserum to adult LDL. Thus, although these authors quote the values as a % of those in adults [adult values : --120 mg/100 ml and -180 mg/100 ml of serum for LDL and HDL, respectively ; Chapman (1980)], calculation showed LDL and HDL levels to be about 80 and 50 mg/100 ml, respectively, in early fetal life (-70 days).…”
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confidence: 99%