Plasma Levels of Catecholamines and Dopamine-β-Hydroxylase

Perioperative catecholamine changes in cardiac risk patients

“…In patients with heart failure, circulating cDA is the highest in concentration of the circulating CAs, usually five-to 10-fold higher than all others, conjugated or free [19,24]. Although the preoperative plasma level of cA was significantly higher in TN↑ than in TN 0 patients, our results show that the preoperative values of cCAs as well as of fCAs in both TN↑ and TN 0 patients were in the physiological range as described for resting healthy volunteers [14,19,23].…”

“…In various studies, enhanced circulating levels of CAs, reflecting systemic sympathetic activation, have been reported in patients during surgical procedures, postoperatively and with acute MI [14,15,22]. It was found that the enhanced plasma concentration of CAs in patients with heart failure seems to be a mixture of fCAs and cCAs as sulphates or glucuronides [16][17][18][19][20].…”

Formation of 8‐iso‐PGF2α and thromboxane A2 by stimulation with several activators of phospholipase A2 in the isolated human umbilical vein

“…Mediators such as bradykinin (BK) and histamine or oxygen free radicals and catecholamines are involved in inflammation and cardiovascular diseases ( Vane & Ferreira, 1978 ; Jean & Bodinier, 1994 ; Kopin, 1989 ). It is well known that BK, histamine, noradrenaline (NA), the divalent cation ionophore A 23187 and hydrogen peroxide (H 2 O 2 ) activate phospholipase A 2 (PLA 2 ) by calcium‐mobilization followed by an increased release of eicosanoids ( Pace‐Asciak & Rangraj, 1977 ; Cherouny et al ., 1988 ; Rao et al ., 1995 ; Schoenberg, 1997 ; Kajiyama et al ., 1990 ; Reddy et al ., 1995 ; Kennedy et al ., 1996 ; Förstermann et al ., 1984 ; Weigel et al ., 1991 ; Juan, 1979 ; Juan & Sametz, 1980 ; Sametz & Juan, 1982 ).…”

Somatostatin receptors and the modulation of adenylyl cyclase activity in Alzheimer's disease.

“…sequence T1-weighted sagittal and axial MRIs (TR = 600 ms; TE = 20 ms, matrix size 256 x 256, scan thickness 5 mm) obtained from a GE [1][2][3][4][5] Tesla super conductive magnet (SignaR) were non-specific and the tumour was not visualised, as the signal intensity of the mass was nearly isointense with the surrounding CSF (fig a).…”