Plasma ionized calcium in hypomagnesaemia.

Zimmet, Paul; Breidahl, H. D.; Nayler, Winifred G.

doi:10.1136/bmj.1.5592.622

Cited by 24 publications

(5 citation statements)

References 9 publications

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“…In normal subjects the plasma calcium concentration falls during an intravenous infusion of magnesium sulphate (Jones and Fourman, 1966). In hypomagnesaemic subjects with associated hypocalcaemia, however, a rise of plasma calcium concentration accompanies magnesium administration (Heaton and Fourman, 1965;Zimmet et al, 1968). Hypomagnesaemia may interfere with the calcium-mobilizing effect of parathyroid hormone on the bone (Heaton and Fourman, 1965), and this would account for the effect of the magnesium infusion on the plasma calcium concentration in our patient.…”

Section: Discussionmentioning

confidence: 75%

Plasma Magnesium Concentration in Primary Hyperparathyroidism

Sutton¹

1970

BMJ

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Section: Discussionmentioning

confidence: 75%

Plasma Magnesium Concentration in Primary Hyperparathyroidism

Sutton¹

1970

BMJ

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“…The present investigation in patients being treated by chronic dialysis was carried out to determine the influence on magnesium metabolism of the magnesium concentration in the dialysate. In addition we wished to verify whether a relationship exists between magnesium and calcium metabolism as claimed by Heaton & Parsons (1961), MacIntyre, Hanna, Booth & Read (1961), Heaton & Pyrah (1963), Alcock & MacIntyre (1962), Clarkson, Warren, McDonald & de Wardener (1967), Bethune, Turpin & Inoue (1968), Zimmet, Breidahl & Nayler (1968) and Martin (1969). Whang & Welt (1963), Heaton (1965), Gitelman, Kukolj & Welt (1968) and Hegsted (1968) had found such correlation to exist in animals.…”

mentioning

confidence: 97%

Magnesium Metabolism in Patients on Regular Dialysis Treatment

et al. 1971

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1. In eight patients being treated by chronic dialysis the relation of magnesium metabolism to the magnesium concentration of the dialysate was investigated. During four periods of 2-6 weeks the magnesium concentrations of the dialysis fluid were 0'44±0'15 mg/IOO ml, 0'70±0'24 mg/IOO ml, 1'83±0'18 mg/IOO ml and 1'97±0'21 mg/IOO ml.2. During all periods the concentration of plasma magnesium and ultrafiltrable magnesium was above normal. The concentration of erythrocyte magnesium was below normal with the lowest concentration in the bath, while all other dialysate concentrations yielded readings above normal values.3. During dialysis the concentration of plasma magnesium and ultrafiltrable magnesium dropped only during the periods with low concentrations of magnesium in the dialysate. During dialysis with the lowest concentration the values for erythrocyte magnesium showed a significant rise whereas with high concentrations the concentration fell significantly. The changes in erythrocyte magnesium proved to be independent of the calcium content of the dialysis fluid.4. The maximum loss of magnesium to the bath solution amounted to 710 mg, with the magnesium content of the bath being only 0'27 mg/IOO ml. The net transfer of magnesium to the blood of the patient amounted to 102 mg with a dialysate magnesium concentration of 1·86 mg/IOO ml. 5. It is concluded that low dialysate magnesium concentrations result in erythrocyte magnesium deficiency whereas high concentrations cause magnesium overloading. A magnesium concentration of 0'7 mg/IOO ml is suggested for the bath solution used in regular dialysis treatment.There are few reported studies on magnesium metabolism in patients on regular dialysis. With a magnesium concentration of more than 1·5 mEq/1 in the dialysate, the concentration of plasma magnesium was usually found to be above normal (

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“…As more calcium is transported into the cells to preserve the iso-electric environment, a relative hypocalcemia produces a tendency towards tetany. 5 Hypomagnesemia and hypokalemia have also been noted to induce tetany. Hypomagnesemia has also been reported during pregnancy and in patients who develop restless leg syndrome.…”

Section: Discussionmentioning

confidence: 97%

Hyperventilation-induced tetany associated with epidural analgesia for labor

Camann

2005

International Journal of Obstetric Anesthesia

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Plasma ionized calcium in hypomagnesaemia.

Cited by 24 publications

References 9 publications

Plasma Magnesium Concentration in Primary Hyperparathyroidism

Plasma Magnesium Concentration in Primary Hyperparathyroidism

Magnesium Metabolism in Patients on Regular Dialysis Treatment

Hyperventilation-induced tetany associated with epidural analgesia for labor

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