Plasma interleukin responses as predictors of outcome stratification in patients after major trauma: a prospective observational two centre study
Matthew Allan Jones,
James Hanison,
Renata Apreutesei
et al.
Abstract:Background and objectivesThere is a need to develop objective risk stratification tools to define efficient care pathways for trauma patients. Biomarker-based point of care testing may strengthen existing clinical tools currently available for this purpose. The dysregulation of pro- and anti-inflammatory cytokines in the pathogenesis of organ failure is well recognised. This study was carried out to evaluate whether blood concentrations of IL-6, IL-10, and IL-6:IL-10 ratios in the early stages of the illness a… Show more
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