Plasma homocysteine level, estradiol level, and brain atrophy: a Mendelian randomization study
Wen Gao,
Wei-Wen Zhu,
Ya-Huan Yu
et al.
Abstract:Objectives
Observational studies link elevated plasma homocysteine (Hcy) with vascular disease. Our aim was to assess the gender difference in the association between the plasma tHcy level and brain atrophy and identify the possible influencer. We employed Mendelian randomization (MR) to explore the causal relationship between plasma tHcy level, estradiol level, and brain atrophy.
Methods
A total of 687 patients with brain at… Show more
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