Plasma homocysteine and total antioxidant status in diabetic chronic kidney disease and diabetic renal allograft recipients: effect of folic acid therapy

Determination of Homocysteine and Lipid Profile Level in the Blood of Chronic Kidney Disease Patients with and without Hemodialysis in Comparison to Normal Healthy Individuals

“…The prevalence of hyperthomocysteinemia in the different age groups of chronic kidney disease patients was evaluated and found that the mean ± SD age in control subjects, CKD with hemodialysis and CKD without hemodialysis was 49.83 ± 5.05, 52.46 ± 5.63 and 50.51 ± 5.39 years in the agematched subjects of different groups with p-value 0.14 respectively. The age-matched findings of different groups by the present study are found consistent to the previous studies [19][20][21]. Serum homocysteine showed highly significant difference among the study groups.…”

“…Frequency of normal, mild and moderate homocysteine in control, CKD with HD and CKD without HD were found as 93.3%, 6.6% and 0%, 6.6%, 50% and 43.3%, 10%, 70% and 20% with p-value of 0.03 respectively. It has been observed that the finding of serum homocysteine (Hcy) noted is consistent to the previous studies [20,22,23]. It has been reported in a study that whether plasma pyridoxal 5 -Phosphate and homocysteine were dependent or independent each other in order to be associated with inflammatory markers in patients with chronic kidney disease (CKD) or those receiving hemodialysis treatment [24].…”