2014
DOI: 10.1186/1546-0096-12-s1-p357
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Plasma exchange therapy for severe gastrointestinal involvement of Henoch Schonlein purpura in children

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Cited by 14 publications
(11 citation statements)
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“…Similarly, a small case series identified patients with severe HSP nephritis who were treated with steroids in combination with plasmapheresis with mixed outcomes [9]. Knowledge about treatment of severe gastrointestinal manifestations come mainly from case reports and series in children, in which immunosuppression and plasmapheresis have been used in the event of steroid failure [10]. …”
Section: Discussionmentioning
confidence: 99%
“…Similarly, a small case series identified patients with severe HSP nephritis who were treated with steroids in combination with plasmapheresis with mixed outcomes [9]. Knowledge about treatment of severe gastrointestinal manifestations come mainly from case reports and series in children, in which immunosuppression and plasmapheresis have been used in the event of steroid failure [10]. …”
Section: Discussionmentioning
confidence: 99%
“…The use of high dose steroids may be considered in HSP patients presenting with severe gastrointestinal (GI) symptoms (i.e., abdominal pain and hematochezia) or persistent proteinuria. If severe GI symptoms or nephrotic syndrome persist despite steroid treatment, then other treatment modalities such as intravenous immunoglobulin (IVIG), immunosuppressive drugs, or plasmapheresis may be used [ 12 13 14 15 16 17 ]. In this study, we investigated the epidemiologic characteristics and clinical courses of children hospitalized with HSP at a tertiary hospital between 2004 and 2015.…”
Section: Introductionmentioning
confidence: 99%
“…Several studies have confirmed low plasma factor XIII levels in IgA vasculitis patients with severe abdominal symptoms, but the underlying mechanisms for the decreased factor XIII activity are unknown. Finally, in cases of IgA vasculitis resistant to corticosteroids and IVIg, plasma exchange and leukocytapheresis have been used [ 27 , 28 ].…”
Section: Discussionmentioning
confidence: 99%