Plasma exchange: an option for the treatment of life-threatening status asthmaticus in pregnancy

Franzen, Douglas; Günther, H.; Borberg, H.; Waßermann, Klaus

doi:10.1034/j.1399-3003.1999.13d40.x

Cited by 4 publications

(3 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In humans, there were no adverse effects of maternal hypercapnia induced for the period of labor [30]. In the published literature, they cited good pregnancy outcomes despite extreme hypercapnia [30][31][32][33]. In our series of 5 pregnant patients with status asthmaticus required intubation, they all had also good maternal outcome but their babies were low birth wieght.…”

Section: Discussionmentioning

confidence: 62%

“…An animal model suggested that maternal hypercapnia (PaCO2 greater than 60 mm Hg) may lead to increased uterine vascular resistance and decreased uteroplacental blood flow [29]. In humans, there were no adverse effects of maternal hypercapnia induced for the period of labor [30]. In the published literature, they cited good pregnancy outcomes despite extreme hypercapnia [30][31][32][33].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Impact of Intensive Care Management of Life Threatening Asthma on Feto-Maternal Outcome

Darwish¹

2014

J Women's Health Care

View full text Add to dashboard Cite

Background: The pregnant patient with medical complications represents a unique challenge to the intensive care specialist and often requires the management expertise of several subspecialists. Aim: to evaluate the impact of intensive care management on the maternal and fetal outcomes in pregnant women with life threatening asthma. Patients and methods: Twenty six obstetric patients with life threatening asthma admitted to the maternal intensive care unit (MICU) of Woman′s Health Hospital during a 2-year Period from January 2010 through May 2012 were included in this study. Data collected included asthma history, ICU management, maternal and fetal outcome. Results: All patients had history of persistent asthma (mild 27%, moderate 50%, severe 13%); most were receiving inhaled β agonist and corticosteroid preparations before the life threatening attack. Five only stopped taking any medications during pregnancy. Controlled mechanical ventilation was required in 5 patients (19%). The severity of hypercapnia ranged from 48 to 82 mm Hg. Two cases had preclampsia, 2 gestational diabetes, vaginal bleeding and premature rupture of membrane in one case and preterm birth in 2 cases. Twenty two cases were delivered by C.S (85%). Conclusions: Obstetric patients with asthma are at risk for the development of life-threatening status asthmaticus, requiring MICU admission. The need for close interdisciplinary communication between obstetricians, intensivist and chest physicians to optimize maternal and fetal outcome is emphasized.

show abstract

Section: Discussionmentioning

confidence: 62%

Section: Discussionmentioning

confidence: 99%

Impact of Intensive Care Management of Life Threatening Asthma on Feto-Maternal Outcome

Darwish¹

2014

J Women's Health Care

View full text Add to dashboard Cite

show abstract

“…These literature reports cite good pregnancy outcomes. 25,[29][30][31] In our series of 5 pregnant patients with status asthmaticus, 4 required intubation. The duration of severe hypercapnia was greater than 24 hours in 4 of our patients.…”

Section: Mechanical Ventilationmentioning

confidence: 74%

Management of the Obstetric Patient with Status Asthmaticus

Elsayegh

Shapiro

2008

J Intensive Care Med

View full text Add to dashboard Cite

Status asthmaticus requiring mechanical ventilation is an uncommon, life-threatening disorder in obstetric patients. The unique physiologic changes of pregnancy, impact of the fetus on the maternal condition, and concerns for fetal and maternal health and survival are particular concerns in critical illness. Furthermore, the issues of hypoxemia and hypercapnia, ventilator management and complications make this disease of respiratory failure an especially important area for review. There is abundant literature on the management of asthma during pregnancy; however the literature is very limited in those with status asthmaticus who require intensive care unit admission. We report our intensive care unit experience in the management of status asthmaticus in 5 pregnant patients and review the literature on management of status asthmaticus during pregnancy.

show abstract

Life-Threatening Asthma

Rajaram¹,

Dellinger²

2008

Critical Care Medicine

View full text Add to dashboard Cite

Plasma exchange: an option for the treatment of life-threatening status asthmaticus in pregnancy

Cited by 4 publications

References 5 publications

Impact of Intensive Care Management of Life Threatening Asthma on Feto-Maternal Outcome

Impact of Intensive Care Management of Life Threatening Asthma on Feto-Maternal Outcome

Management of the Obstetric Patient with Status Asthmaticus

Life-Threatening Asthma

Contact Info

Product

Resources

About