Plasma corticosteroid‐binding globulin concentrations are preserved in mild cirrhosis

Author's reply: Plasma corticosteroid‐binding globulin levels in cirrhosis

“…

To the Editor, We thank Dr. Lee and colleagues for their interest in our systematic review and meta-analysis on relative adrenal insufficiency (RAI) in cirrhosis 1 and wish to comment on their letter. 2 We agree that total cortisol (TC) levels are an imperfect assessment of patient adrenal function in cirrhosis given their dependence on the availability of liver-derived binding proteins. This is high-

…”