Plasma cell granuloma of the maxillary sinus: A case report and literature review

Abstract

Review of the literature indicates that the optimal first line of treatment is high-dose corticosteroids. Surgery is indicated if the lesion fails to respond. Radiotherapy is indicated if complete resection is not feasible.

Maxillary Inflammatory Myofibroblastic Tumor

“…Autoimmunity has also been considered as an etiological factor. Chronic infection or inflammation leading to differentiation of plasma cells is another theory [1,2,5,7]. In our case, the history of tuberculous lymphadenitis (chronic granulomatous disease), although treated and cured maybe considered as a trigger based on the chronic inflammatory theory.…”

“…Keen et al suggested perineurofibromatosis and Du Vuysere et al suggested perineural invasion as the causative pathogenesis for neural symptoms of IMT. Our patient presented with hemifacial pain and ptosis which can be attributable to infraorbital nerve and oculomotor nerve involvement by the tumor [1,3,5,6,8,9].…”

“…Antiactin antibody positivity denotes its origin in the muscle. It is immunohistochemically negative to CD68, keratin, desmin, S-100, and caldesmon [1,3,5,6,9].…”

“…The common sites of occurrence are the abdomen and pelvis. However, it can occur in the peritoneum, central nervous system, bone, and uterus [2][3][4][5][6]. In the head and neck region, the most common site of occurrence is the orbit.…”

“…vocal folds, oral cavity, and oropharynx, nasopharynx, parapharyngeal space, and paranasal sinuses [2,3,5]. It does not occur in a specific age group, although literature reveals a median age group of 47.4 years for the occurrence.…”