Plasma-cell granuloma of the fourth ventricle

Maeda, Yasuhiro; Tani, Eiichi; Nakano, Masaru; Matsumoto, Tsuyoshi

doi:10.3171/jns.1984.60.6.1291

Cited by 49 publications

(29 citation statements)

References 23 publications

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“…Although lesions closely corresponding to Gagel granuloma have not been previously considered in other regions of the body, light, ultrastructural and immunohistological observations in our patients are similar to those described in other cases of plasma-cell granuloma (Kuzela 11 ;Toccanier et al 15;Leonardo and Palestro 12, 1978;Maeda et al ~). Hence, on the basis of the present results, it can be postulated that the socalled Gagel type of granuloma is probably a plasmacell granuloma of the neurohypophysis and hypotha-!amic region.…”

Section: Discussionsupporting

confidence: 70%

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Plasma cell granuloma of the hypothalamic region

et al. 1989

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Two patients suffering from diabetes insipidus, with additional symptoms of impaired vision and signs of panhypopituitarism and increased intracranial pressure, showed a normal sella tursica in the X-ray examination of the skull but large, dense space-occupying lesions in the hypothalamus on CT scans of the brain. NMR performed in one patient disclosed suprasellar growth of a hypothalamic lesion. Proliferation of lymphoplasmocytes and mature plasma cells was seen by light microscopic and electromicroscopical examination of biopsy samples in both cases; histiocytes and multinucleated giant cells were absent; tuberculosis, syphilis and sarcoidosis were ruled out by appropriate tests. Plasma cells exhibited polyclonal immunoglobulin expression as revealed by immunocytochemistry using the PAP method. Taken together these features are typical of plasma cell granuloma. Transitory remission after radiotherapy was obtained in one patient.

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Section: Discussionsupporting

confidence: 70%

“…Only three patients have been reported so far; lesions in these cases were located in the meninges of the spinal cord. (Eimoto etal.4), tentorium (West et al 16) and fourth ventricle (Maeda et al 13). Here we report on two further patients with plasma-cell granuloma of the hypothalamic region.…”

Section: Introductionmentioning

confidence: 99%

Plasma cell granuloma of the hypothalamic region

et al. 1989

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“…[6][7][8] However, inflammatory pseudotumors of the spleen are extremely rare, with only 67 cases, including our own, ever reported. When the lesion occurs as a primary splenic tumor, lymphoma is usually clinically suspected, and the true diagnosis is usually only revealed after the spleen is examined histologically.…”

Section: Introductionmentioning

confidence: 99%

Inflammatory pseudotumor of the spleen: Report of a case

2000

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A case of a 45-year-old Japanese man with a splenic inflammatory pseudotumor is described. This benign lesion is rarely reported in the world literature. We preoperatively could not rule out the possibility of a malignant neoplasm, due to the fact that the tumor had grown in size after a 2-year observation. However, after performing a splenectomy, a histological examination of the mass revealed an inflammatory process. Inflammatory pseudotumors often pose diagnostic difficulties because the clinical and radiological findings tend to suggest a malignancy. The clinical and pathological features of such previously reported cases are also reviewed.

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“…4 Intracranial plasma-cell granuloma become symptomatic when the adjacent brain is compressed; surgical excision has been the treatment of choice. 5 In some reported patients with subtotal resection or recurrence, irradiation 6,7 or steroid treatment 6 has been used. However, the efficacy is unclear to date.…”

Section: Discussionmentioning

confidence: 99%