Plasma Cell Granuloma in Buccal Mucosa: A Case Report and Review of Different Case Reports on Plasma Cell Granuloma in Oral Cavity

Abstract

Introduction: 3 Plasma cell granuloma mainly occurs in lungs but can occur in any other organ or soft tissue . It occurs very rarely in oral cavity. We have also reviewed different articles describing plasma cell granuloma in oral cavity. We search the articles in google scholar and pubmed with keywords plasma cell granuloma in oral cavity, buccal mucosa, gingiva, tongue. A Case report: 39 year old male came with a chief complaint of growth on left buccal mucosa. HPE discovered parakeratinized stratied squamous epithelium, showing focal ulceration and underlying dense connective tissue stroma. On the basis of clinicopathological ndings the diagnosis of plasma cell granuloma was made. Discussion: Plasma cell granuloma is a benign lesion but its exact aetiology, behaviour and prognosis is not completely known. We can give emphasis on frozen histopathology intraoperatively to avoid unnecessarily extensive and potentially destructive surgery as the treatment plan.

Clinicopathological Study of Oral Plasma Cell Granuloma

“…Mostly, they have been recorded as single case reports. Oral plasma cell granuloma has been represented in the tongue, 5 lip, 6 oral mucosa, 1 and gingiva. 7,16 The demographic data analysis of the current study groups of OPCG revealed that the ages were found to range from 11 to 73 years with a mean of 42.40 years.…”

“…A plasma cell's main function is to produce immunoglobulin's or antibodies. 1 Plasma cell granuloma (PCG) is a rare benign tumor-like condition that showed proliferation of spindle cells with marked inflammatory infiltrates composed predominantly of pcs and small lymphocytes. Although it occurs most commonly in the lungs, 2 extra pulmonary presentation of PCG was reported to affect other organs such as the vagina, bladder, and the abdominal cavity.…”

“…Oral plasma cell granuloma has been reported to be rarely seen in the oral cavity, as a single unilateral swelling seen primarily on the periodontal tissue, mainly the gingiva, 4 followed by the tongue, 5 lips, 6 buccal and oral mucosa. 1 These lesions have been observed to have no gender predilection and might occur at any age. 7 The reported cases of OPCG were in the wide range of 19 months to 63 years old, but most of the reported cases are observed in the fourth and fifth decades of life with female predominance.…”