Plasma B‐type natriuretic peptide levels in children with heart disease

Knirsch, Walter; Häusermann, Eliane; Fasnacht, Margrit; Hersberger, Martin; Gessler, Peter; Bauersfeld, Urs

doi:10.1111/j.1651-2227.2011.02258.x

Cited by 24 publications

(16 citation statements)

References 23 publications

(27 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Plasma BNP levels are elevated in adults and children with heart disease and PAH (idiopathic or congenital), so these levels serve as a useful laboratory parameter in medical or surgical treatment [23,24]. In our study we showed that all of the PAH patients had elevated levels of plasma BNP.…”

Section: Discussionsupporting

confidence: 58%

The Effects of Perioperative Inhaled Iloprost on Pulmonary Hypertension with Congenital Heart Disease

et al. 2013

View full text Add to dashboard Cite

Objectives: The treatment of choice for congenital heart disease (CHD) with pulmonary arterial hypertension (PAH) is still controversial. We assessed the efficacy and safety of perioperative inhaled iloprost therapy in CHD with PAH. Methods: Among 45 patients with a ventricular septal defect and/or an atrial septal defect with PAH, 28 patients were treated with inhaled iloprost before and after surgery. Perioperative clinical parameters and plasma B-type natriuretic peptide (BNP) were evaluated. Results: No statistical difference in the estimated right ventricular systolic pressure (e-RVP), the e-RVP-to-systemic pressure ratio, and preoperative BNP levels between the iloprost group and the control group were found. Among the iloprost group, oxygen saturation was increased significantly after iloprost inhalation therapy (p = 0.0052). The iloprost group was also significantly correlated with less use of inhaled nitric oxide in the immediate postoperative period compared to the control group (p = 0.021). The durations of mechanical ventilation (p = 0.018), ICU stay (p = 0.005), and chest tube use (p = 0.039) were significantly shorter in the iloprost group compared to the control group. The plasma BNP, checked on 7th day of postoperatively, was lower in the iloprost group than in the control group (p = 0.008). Conclusion: Perioperative inhaled iloprost therapy showed the benefit of cardiac functional improvement and early weaning of postoperative supportive care in the management of CHD with PAH.

show abstract

Section: Discussionsupporting

confidence: 58%

The Effects of Perioperative Inhaled Iloprost on Pulmonary Hypertension with Congenital Heart Disease

et al. 2013

View full text Add to dashboard Cite

show abstract

“…It plays an important role in the diagnosis and prognosis assessment of this disease, and it is regarded as a specific serum marker and gold standard for CHF diagnosis in recently years. [5][6][7] Carvedilol is a third-generation b-blocker, and clinical trials demonstrated that it can significantly improve the clinical symptoms, prognosis, and survival of patients with CHF. 8,9 This study aimed to observe the changes of serum h-FABP, BNP, and cardiac function before and after treatment with carvedilol in children with CHF and to explore the clinical application of h-FABP, BNP, and the therapeutic effect of carvedilol in children with chronic cardiac insufficiency.…”

Section: Introductionmentioning

confidence: 99%

Effect of Carvedilol on Serum Heart-type Fatty Acid-binding Protein, Brain Natriuretic Peptide, and Cardiac Function in Patients With Chronic Heart Failure

Sun

Wei

S.K.

et al. 2015

Journal of Cardiovascular Pharmacology

View full text Add to dashboard Cite

show abstract

“…In patients with structural CHD the range of NP levels varies widely depending on a number of factors including age at time of surgery, type of lesion, stage and type of palliation and duration of CPB (11)(12)(13)26).…”

Section: Discussionmentioning

confidence: 99%

Clinical utility of B‐type natriuretic peptide (NP) in pediatric cardiac surgery – a systematic review

Afshani

Schulein

Biccard

et al. 2014

Pediatric Anesthesia

View full text Add to dashboard Cite

show abstract

Plasma B‐type natriuretic peptide levels in children with heart disease

Abstract: Plasma BNP levels are elevated in children with heart disease before treatment and are a useful laboratory parameter under treatment during long-term follow-up.

Cited by 24 publications

References 23 publications

The Effects of Perioperative Inhaled Iloprost on Pulmonary Hypertension with Congenital Heart Disease

The Effects of Perioperative Inhaled Iloprost on Pulmonary Hypertension with Congenital Heart Disease

Effect of Carvedilol on Serum Heart-type Fatty Acid-binding Protein, Brain Natriuretic Peptide, and Cardiac Function in Patients With Chronic Heart Failure

Clinical utility of B‐type natriuretic peptide (NP) in pediatric cardiac surgery – a systematic review

Contact Info

Product

Resources

About