2020
DOI: 10.21203/rs.2.23405/v1
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Plasma APRIL as a Potential Biomarker in the Diagnosis of Obstructive Sleep Apnea

Abstract: Background: Obstructive sleep apnea (OSA) is the most common type of sleep breathing disorder and is characterized by chronic intermittent hypoxia, which could cause inflammation and NF-KB-dependent inflammatory pathways activation. Circulating APRIL might play an important role in promoting inflammation and NF-KB-dependent inflammatory pathways activation. We explored the role of APRIL as a potential mechanism of inflammation in OSA patients. Methods: After detailed sleep evaluated, venous blood and demograph… Show more

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