Plasma anti-Müllerian hormone as a biomarker for bovine granulosa-theca cell tumors: Comparison with immunoreactive inhibin and ovarian steroid concentrations

Ali, Hesham A.; Kitahara, Go; Nibe, Kazumi; Yamaguchi, Ryoji; Horii, Yoichiro; Zaabel, Samy; Osawa, Takeshi

doi:10.1016/j.theriogenology.2013.07.022

Cited by 40 publications

(51 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Under field conditions, although the clinical cure of GCTs seems to be determined that the cow become pregnant in the previous report (Leder et al 1988;Haneishi et al 2008), we determined more certainly by confirming both pregnancy (recovery of fertility) and reduction in AMH concentration in this report. It was reported that the immunoreactive AMH expressed in the neoplastic granulosa cells with high blood AMH levels, and blood AMH levels had declined to normal concentrations within a week after surgical extraction of GCTs (Kitahara et al 2012;El-Sheikh Ali et al 2013). The finding of this report is comparable with the above studies that the elevated the plasma AMH concentration declines after surgical removal of the affected ovary.…”

Section: Discussionsupporting

confidence: 86%

“…The plasma AMH concentration of this report was markedly higher than that of above report. Indeed, in previous reports, the plasma AMH concentrations in cows with GCTs have shown a wider range (0.36-481.07 ng/ml) (Kitahara et al 2012;El-Sheikh Ali et al 2013;El-Sheikh Ali et al 2015). Thus, it seems to be controversial about the diagnostic levels of AMH concentrations for bovine GCTs.…”

Section: Discussionmentioning

confidence: 98%

“…Similarly, in cattle, the measurement of plasma AMH concentration was identified as a more reliable and sensitive method to diagnose GCTs than that of the measurement of INH or ovarian steroids (Kitahara et al 2012). The cut-off diagnostic concentration of plasma AMH in GCTsaffected cattle is identified as >0.36 ng/ml (El-Sheikh Ali et al 2013). This report provides the information on clinical diagnosis of GCTs based on measurement of plasma AMH concentrations before surgical extraction of affected ovary, and the artificial insemination (AI) afterwards resulted in the cow pregnancy.…”

Section: Introductionmentioning

confidence: 98%

See 2 more Smart Citations

Clinical diagnosis of bovine granulosa cell tumour in a Holstein cow using plasma anti-Müllerian hormone concentration: a case report

Okawa

Tomiki

Ishida³

et al. 2016

Journal of Applied Animal Research

View full text Add to dashboard Cite

A 23-month-old Holstein cow had a multi-cystic and enlarged left ovary detected by rectal palpation and ultrasonography. The plasma anti-Müllerian hormone (AMH) concentration was 36.5 ng/ml, which is higher than normal. From the clinical history and plasma AMH levels, a granulosa cell tumour (GCT) was diagnosed. Affected ovary was removed by ovariectomy, and GCT was confirmed with histopathological findings. The cow was artificially inseminated at 145 days after ovariectomy, and conceived. The plasma AMH concentration declined at 224 days after removal of affected ovary to less than 0.1 ng/ml, and recovery of fertility was achieved. In conclusion, measurement of plasma AMH levels combined with rectal palpation and ultrasonography examinations could be useful in clinical diagnosis of bovine GCT. ARTICLE HISTORY

show abstract

Section: Discussionsupporting

confidence: 86%

Section: Discussionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 98%

See 1 more Smart Citation

Clinical diagnosis of bovine granulosa cell tumour in a Holstein cow using plasma anti-Müllerian hormone concentration: a case report

Okawa

Tomiki

Ishida³

et al. 2016

Journal of Applied Animal Research

View full text Add to dashboard Cite

show abstract

“…The microscopic examination performed on the fragments of four ovarian tumours found in this study revealed that in three cases, it was the Granulosa Cell Tumour (GCT), which is a type of sex cord-stromal tumour, composed primarily of neoplastic granulosa cells [32] , and it is the most common bovine ovarian tumour in cattle [32][33][34][35] . In one case, it was the cystadenoma.…”

Section: Discussionmentioning

confidence: 99%

Cezayir’de El-Harrach Kesimevinde Kesilen İneklerdeki Genital Kanal Patolojileri

Mimoune¹,

Kaidi²,

Azzouz³

et al. 2016

Kafkas Univ Vet Fak Derg

View full text Add to dashboard Cite

The aim of this study was to determine genital organ disorders in 2025 cows at El-Harrach abattoir in the capital of Algeria and to describe the microscopic changes associated with these cases. The results obtained showed a high incidence of slaughtered pregnant cows (16.49%). Majority of these cases were at the early gestation. The most frequently encountered defects were ovarian cyst, uterine infection, and inflammatory salpinx, which proved that contamination and infection are always present in the cowsheds from where animals were brought. Other observed abnormalities were cervicitis, mucometra, double cervix, unicornis uterus, horn malformation, uterine tumour, triple cervix (which is a new finding in the world), salpinx adhesion, pyosalpinx, hydrosalpinx, ovarobursal adhesion, ovarian inactivity, ovarian inflammatory changes, ovarian tumour and parovarian cysts. ÖzetBu çalışmanın amacı Cezayir'in başşehrinde yer alan El-Harrach kesimevinde kesilen 2025 inekte gözlenen genital kanal bozukluklarını belirlemek ve bu vakalarla alakalı mikroskopik değişiklikleri tanımlamaktır. Sonuçlar çok sayıda gebe hayvanın (%16.49) kesime gönderildiğini ortaya koymuştur. Bu vakaların da çoğu gebeliğin erken dönemlerindeydi. En sık karşılaşılan bozukluklar ovaryum kistleri, uterus enfeksiyonu ve salfinks yangısıydı. Bu durum kesim için getirilen hayvanların getirildikleri ahırlarda enfeksiyonun ve kontaminasyonun sürekli olduğunu göstermekteydi. Diğer gözlenen bozukluklar servisitis, mukometra, çift serviks, unicornis uterus, rahim boynuz malformasyonları, uterus tümörü, triple serviks (yeni bir bulgu olarak), salfinks yapışması, pyosalfinks, hidrosalfinks, ovarobursal yapışma, ovaryum inaktivitesi, ovaryumun yangısal değişimleri, ovaryum tümörü ve parovarian kistler olarak kaydedildi.

show abstract

“…In males, AMH is produced by the Sertoli cell [5]. Anti-Müllerian hormone assays have also been used to evaluate fertility and gonadal pathology in humans and domestic animals [6][7][8][9][10]. In women, serum AMH concentrations decrease with age, independently of the menstrual cycle and the number of pregnancies [7].…”

Section: Introductionmentioning

confidence: 99%

Concentrations of anti-Müllerian hormone in the domestic cat. Relation with spay or neuter status and serum estradiol

Axnér

Holst

2015

Theriogenology

View full text Add to dashboard Cite

Plasma anti-Müllerian hormone as a biomarker for bovine granulosa-theca cell tumors: Comparison with immunoreactive inhibin and ovarian steroid concentrations

Cited by 40 publications

References 38 publications

Clinical diagnosis of bovine granulosa cell tumour in a Holstein cow using plasma anti-Müllerian hormone concentration: a case report

Clinical diagnosis of bovine granulosa cell tumour in a Holstein cow using plasma anti-Müllerian hormone concentration: a case report

Cezayir’de El-Harrach Kesimevinde Kesilen İneklerdeki Genital Kanal Patolojileri

Concentrations of anti-Müllerian hormone in the domestic cat. Relation with spay or neuter status and serum estradiol

Contact Info

Product

Resources

About