Plasma and Nanomaterials: Fabrication and Biomedical Applications

Abstract

Application of plasma medicine has been actively explored during last several years. Treating every type of cancer remains a difficult task for medical personnel due to the wide variety of cancer cell selectivity. Research in advanced plasma physics has led to the development of different types of non-thermal plasma devices, such as plasma jets, and dielectric barrier discharges. Non-thermal plasma generates many charged particles and reactive species when brought into contact with biological samples. The main constituents include reactive nitrogen species, reactive oxygen species, and plasma ultra-violets. These species can be applied to synthesize biologically important nanomaterials or can be used with nanomaterials for various kinds of biomedical applications to improve human health. This review reports recent updates on plasma-based synthesis of biologically important nanomaterials and synergy of plasma with nanomaterials for various kind of biological applications.

Evolving Technologies and Strategies for Combating Antibacterial Resistance in the Advent of the Postantibiotic Era

“…The possible acting of CAP and NP can meet the challenges of this battle. The first one is the production and synthesis of antibacterial NPs that are known as plasma nanoscience 100. In general, plasma nanoscience focuses on the specific roles and benefits of the ionized gas (plasma) environments in assembling, processing, and controlling nanoscale (including biological) objects 186.…”

“…In terms of nanoparticle production by CAP treatment, CAP‐generated RNOS could be encapsulated in nanomaterials that will increase the lifetimes and penetration capabilities of RONS for applications. The encapsulation of RNOS generating sources can also be encapsulated in particular NP designs, whose antibacterial activities can be CAP coded 100,187. In addition to these practices in creating plasma‐nanoparticle synergy as an antibacterial strategy, plasma modification of NP with plasma polymerization approach is employed as a promising strategy to provide nonagglomerated NP that can provide biocompatible and more effective antibacterial treatments compared to their nonmodified counterparts 188.…”

“…The species formed with CAP can be applied to synthesize biologically important nanomaterials or can be used with nanomaterials for antibacterial treatments 100. Recently, researches have been using plasma technology as a prominent “green” synthesis method for nanomaterials and investigating their antibacterial properties 101.…”

“…Recently, researches have been using plasma technology as a prominent “green” synthesis method for nanomaterials and investigating their antibacterial properties 101. A combination of nanomaterials and cold plasma is also gaining attention in order to provide synergistic effects and better treatment efficiency in biomedical applications 100,102. In medical applications of CAP and NP for antibacterial treatments, synergetic effects in terms of reactivity, selectivity against pathogens, their toxicity to healthy cells and tissues, and their penetration to the lesion site regions are aimed for.…”

Controlled Release of 5‐Fluorouracil from Alginate Hydrogels by Cold HMDSO−Plasma Surface Engineering

“…In a bid to develop more efficient hydrogels, tailoring the surface properties has evolved into an attractive strategy and the use of cold atmospheric plasma (CAP) has gained an upward thrust significantly . Researchers are currently warming up to the idea of fabrication of hydrophobic surfaces by CAP treatment for anti‐icing, anti‐fogging, anti‐corrosion, anti‐biofouling and anti‐friction properties .…”