Plaque‐like cutaneous mucinosis after joint replacement

Plaque‐like cutaneous mucinosis of childhood

“…Nevertheless, there is a striking clinical heterogeneity in these reports. 3,4 In fact, PCM could be probably a heterogeneous group of disorders characterized by mucin accumulation in the dermis, rather than a single condition. 5…”

“…5,6 The clinical appearance of PCM in adults, however, is more heterogeneous and may look different from our patient's. 3,4 The term PCM encompasses a wide and variable spectrum of clinical manifestations such as erythematous urticarial papules, slightly elevated plaques with telangiectasia, infiltrated nodular plaques, or an extensive cutaneous infiltration. [2][3][4]7,8 The distribution of skin lesions in adult PCM differs among published cases affecting the midback and chest, but also other parts of the body such as the shoulders, scalp, forehead, or knee.…”

“…3,4 The term PCM encompasses a wide and variable spectrum of clinical manifestations such as erythematous urticarial papules, slightly elevated plaques with telangiectasia, infiltrated nodular plaques, or an extensive cutaneous infiltration. [2][3][4]7,8 The distribution of skin lesions in adult PCM differs among published cases affecting the midback and chest, but also other parts of the body such as the shoulders, scalp, forehead, or knee. 4,5,8 Therefore, the skin features in children's PCM appear to differ from adult PCM in appearance, configuration, and distribution, thus raising the possibility that pediatric PCM is a different and better defined condition.…”

Focal cutaneous mucinosis after knee replacement: A rare entity successfully treated with intralesional polidocanol

“…However, the pathogenesis of cutaneous mucin deposition after joint replacement surgery is still unclear, although several mechanisms have been considered: increased secretion of hyaluronic acid from osteoarthritic joints, local reactive process to foreign body (prosthesis), accidental implantation of the synovial cells at the surgical site, or traumatic damage of the lymphatic system responsible for the drainage and absorption of the synovial fluid 2, 3, 4, 8…”

“…There is a paucity of published cases of cutaneous mucinosis developing adjacent to replaced joints 3, 4. Apart from presenting our patient, we review the literature, propose the pathogenesis, and suggest treatment for this unusual cutaneous presentation.…”