Plaque Characteristics in Culprit Lesions and Inflammatory Status in Diabetic Acute Coronary Syndrome Patients

Abstract

Diabetic patients with ACS have more plaques with characteristics of plaque vulnerability, different composition of plaques, and have increased inflammatory status compared with nondiabetic patients with ACS.

Coronary Plaque Characteristics in Patients With Diabetes Mellitus Who Presented With Acute Coronary Syndromes

“…Moreover, poorly controlled DM is associated with a greater lipid burden 18. Intravascular ultrasound studies have shown that patients with DM and ACS have greater plaque burden and necrotic core volume at the culprit lesions compared with patients with ACS but not DM 20, 21. In contrast, previous OCT studies did not demonstrate the differences in the prevalence of lipid‐rich plaque or TCFA at the culprit lesion 6, 8, 22, 23.…”

Relationship between type 2 diabetes mellitus and coronary artery lesion characteristics: a single center study

“…4 It has been shown that diabetic patients have more plaques, which appeared to have characteristics of plaque vulnerability and a different composition of plaques than nondiabetic patients for those presenting with acute coronary syndrome (ACS). 5 Diabetic patients have more triple-vessel and less single-vessel CAD than nondiabetics. 6 The aim of this study was to assess the plaque characteristics in …”

iMap-Intravascular Ultrasound Radiofrequency Signal Analysis Reflects Plaque Components of Optical Coherence Tomography-Derived Thin-Cap Fibroatheroma

“…25 Others have reported the usefulness of volumetric VH-IVUS analysis using more many frames per entire target lesion. 26 In contrast, the methodology of frame analysis to identify TCFA in iMap-IVUS analysis has not been established, because iMap-IVUS and pathological findings have not been fully validated. In addition, volume analysis is difficult to apply in the clinical setting because it is time-consuming, labor intensive and requires specialist training.…”