Plants as a natural resource of bioactive compounds for drug formulation to control infectious diseases

Abstract

In recent years, plants derived phytochemicals attracting interest of researchers due to the antimicrobial/antibacterial resistance of the antibiotic drugs against several diseases; as medications from medicinal plants are safe, effective, easily available and infrequently accompanied. This review, highlighted significance of the secondary metabolites and their mode of action. Drug discovery using natural products is a challenging task for designing new leads. It describes the bioactive compounds derived from natural resources, its phytochemical analysis, characterization and pharmacological investigation. It focuses on the success of these resources in the process of finding and discovering new and effective drug compounds that can be useful for controlling infectious diseases. From many years, natural products have been acting as a source of therapeutic agents and have shown beneficial uses. The phytochemical screening of several plants using advanced analytical techniques showed that plants act as resource of antioxidant, antibacterial, antiviral, antiinflammatory compounds which can take the place of modern medications in controlling microbial diseases. Furthermore; The extract of plant's leaves, root or stem showed high scavenging properties related to free radical generation. It was concluded that only natural product drug discovery may plays an important role for formulation of new drugs to develop the scientific evidence of these natural resources. Current review highlighting the significance of the plant derives bioactive compounds and their action against different diseases.

Biological Activities Of A Local Plant I. Viscosa From The Kabylia Of Algeria

“…They can prevent the moieties and scavenge the free radicals. They also play vital roles in inhibiting the pathogenic processes linked to severe diseases like cancer, cardiovascular disease, macular degeneration, cataracts, and asthma, enhancing immune function (Akram et al, 2021). These compounds protect the cell damages by free radicals, released as byproducts of regular metabolism (Naz et al, 2021).…”