Plantas medicinais no controle de urolitíase

Cruces, I.L; Patelli, Thais Helena Constantino; Tashima, Cristiano Massao; Mello-Peixoto, Erika Cosendey Toledo de

doi:10.1590/s1516-05722013000500020

Cited by 12 publications

(19 citation statements)

References 49 publications

(50 reference statements)

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“…No entanto, o percentual de êxito varia de acordo com a região geográfica e/ou outros fatores como o estado civil, a presença de doenças psicológicas ou psiquiátricas ou grau de nicotino-dependência (MALBERGIER; OLIVEIRA Jr., , CARAM et al, 2009VANNUCHI;SECCO, 2011, BRASIL, 2016 , FRANÇA et al, 2015, BAIOTTO et al, 2016, KOCK et al, 2017 (CRUCES et al, 2013;SOUZA et al, 2014).…”

Section: Discussionunclassified

Análise Retrospectiva Do Uso De Antirretrovirais Para Hiv Em Pacientes De Uma Unidade De Saúde Em Anápolis-Go

Araújo¹,

Lima²

2019

Ciências Da Saúde

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Section: Discussionunclassified

Análise Retrospectiva Do Uso De Antirretrovirais Para Hiv Em Pacientes De Uma Unidade De Saúde Em Anápolis-Go

Araújo¹,

Lima²

2019

Ciências Da Saúde

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“…Several authors recommended some diet interventions for reducing the risk of urinary stone formation and its recurrence but there is no conclusive consensus in the literature regarding the effectiveness of dietary interventions and recommendations about specific diets for patients with urinary calculi (5). On the other hand, the use of medicinal plants and nutraceuticals have long been used worldwide for the management of recurrence in patients affected by urinary stones (6). Ettinger et al, published in 1997 one of the first clinical trial on the use of potassium-magnesium citrate in preventing recurrent calcium oxalate kidney calculi, demonstrating that potassium-magnesium citrate effectively prevents recurrent calcium oxalate stones (7).…”

Section: Original Papermentioning

confidence: 99%

Phyllanthus niruri and Chrysanthellum americanum in association with potassium and magnesium citrates are able to prevent symptomatic episode in patients affected by recurrent urinary stones: A prospective study

Cai

Tiscione

Puglisi

et al. 2021

Arch Ital Urol Androl

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Objective: The aim of this study is to evaluate the efficacy of a food supplement containing Phyllanthus niruri and Chrysanthellum americanum in association with potassium and magnesium citrates in the treatment and prophylaxis of urinary stones. Materials and methods: Eighty-two patients (mean age 49.7 ± 11.2) with history of urinary stones received this food supplement, one capsule a day for 6 months. Each administration contained a combination of the following ingredients: 244 mg Potassium citrate, 735 mg Magnesium citrate, Phyllanthus (Phyllantus niruri) herb d.e. 15% mg Tannins 220 mg, Chrysanthellum (Chrysanthellum americanum Vatke) plant d.e. ¼ 55 mg. After 6 months, all patients underwent urologic visit, urinalysis, imaging and quality of life (QoL) questionnaires evaluation. Each patient was also evaluated by computed tomography (CT) scan at baseline and at 6 months. Result: From January 2018 to March 2019, 82 patients (mean age 49.7 ± 11.2) completed the follow-up period and were analyzed. Fifty patients showed lower stone dimensions (60.9%). The average stone size was 0.9 mm, with a significant reduction in comparison with the baseline (-6.7 mm ± 3 mm) (p < 0.001). Forty-nine patients (59.7%) did not show any symptomatic episode with an improving in QoL (+0.4 ± 0.1) (p < 0.001) in comparison with the baseline. At the end of the follow-up period, 27 patients out of 82 were stone-free (32.9%). Moreover, we report a significant reduction of patients with asymptomatic bacteriuria (ABU) between the baseline and the end of the follow-up evaluation (p < 0.001). Conclusions: In conclusion, this food supplement is able to improve quality of life in patients with urinary stones, reducing symptomatic episodes and the prevalence of ABU.

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“…In addition to conventional treatment for lithiasis, medicinal plants have long been used worldwide ( 6 ). Phyllanthus niruri or “stone breaker tea” is one such natural alternative that is inexpensive, easy to obtain and has a low incidence of adverse effects ( 7 ).…”

Section: Introductionmentioning

confidence: 99%

Effect of phyllanthus niruri on metabolic parameters of patients with kidney stone: a perspective for disease prevention

et al. 2018

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Phyllanthus niruri (P.niruri) or stone breaker is a plant commonly used to reduce stone risk, however, clinical studies on this issue are lacking.Objective:To prospectively evaluate the effect of P. niruri on the urinary metabolic parameters of patients with urinary lithiasis.Materials and Methods:We studied 56 patients with kidney stones <10mm. Clinical, metabolic, and ultrasonography assessment was conducted before (baseline) the use of P. niruri infusion for 12-weeks (P. niruri) and after a 12-week (wash out) Statistical analysis included ANOVA for repeated measures and Tukey's/McNemar's test for categorical variables. Significance was set at 5%.Results:Mean age was 44±9.2 and BMI was 27.2±4.4kg/m2. Thirty-six patients (64%) were women. There were no significant changes in all periods for anthropometric and several serum measurements, including total blood count, creatinine, uric acid, sodium, potassium, calcium, urine volume and pH; a significant increase in urinary potassium from 50.5±20.4 to 56.2±21.8 mg/24-hour (p=0.017); magnesium/creatinine ratio 58±22.5 to 69.1±28.6mg/gCr24-hour (p=0.013) and potassium/creatinine ratio 39.3±15.1 to 51.3±34.7mg/gCr24-hour (p=0.008) from baseline to wash out. The kidney stones decreased from 3.2±2 to 2.0±2per patient (p<0.001). In hyperoxaluria patients, urinary oxalate reduced from 59.0±11.7 to 28.8±16.0mg/24-hour (p=0.0002), and in hyperuricosuria there was a decrease in urinary uric acid from 0.77±0.22 to 0.54±0.07mg/24-hour (p=0.0057).Conclusions: P.niruri intake is safe and does not cause significant adverse effects on serum metabolic parameters. It increases urinary excretion of magnesium and potassium caused a significant decrease in urinary oxalate and uric acid in patients with hyperoxaluria and hyperuricosuria. The consumption of P.niruri contributed to the elimination of urinary calculi.

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Plantas medicinais no controle de urolitíase

Cited by 12 publications

References 49 publications

Análise Retrospectiva Do Uso De Antirretrovirais Para Hiv Em Pacientes De Uma Unidade De Saúde Em Anápolis-Go

Análise Retrospectiva Do Uso De Antirretrovirais Para Hiv Em Pacientes De Uma Unidade De Saúde Em Anápolis-Go

Phyllanthus niruri and Chrysanthellum americanum in association with potassium and magnesium citrates are able to prevent symptomatic episode in patients affected by recurrent urinary stones: A prospective study

Effect of phyllanthus niruri on metabolic parameters of patients with kidney stone: a perspective for disease prevention

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