Plant mitogen-activated protein kinase signaling cascades

Tena, Guillaume; Asai, Tomohisa; Chiu, Wan-Ling; Sheen, Jen

doi:10.1016/s1369-5266(00)00191-6

Cited by 450 publications

(372 citation statements)

References 49 publications

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“…Recent studies of MAPKs other than SIPK and WIPK have pointed to their critical roles in mediating plant stress responses (Tena et al, 2001;Zhang and Klessig, 2001;Pedley and Martin, 2005). We chose several MAPK genes that have been shown to be involved in early responses within the N. attenuata-M. sexta interaction and measured their transcript levels in both UT and AZ using quantitative realtime PCR (qRT-PCR).…”

Section: Mapk Genes Have Different Transcript Levels In Ut and Az Plantsmentioning

confidence: 99%

A Comparison of Two Nicotiana attenuata Accessions Reveals Large Differences in Signaling Induced by Oral Secretions of the Specialist Herbivore Manduca sexta

Hettenhausen

Schuman

et al. 2008

Plant Physiology

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Genetic variation within and among populations provides the raw material for evolution. Although many studies describe inter-and intraspecific variation of defensive metabolites, little is known about variation among plant populations within early signaling responses elicited by herbivory or by herbivore oral secretions (OS) introduced into wounds during feeding. In this study, we compare the OS-elicited early responses as well as the antiherbivore defensive metabolites in two accessions of the wild tobacco Nicotiana attenuata and show that, compared with an accession collected from Utah, an Arizona accession has lower herbivore-elicited activity of the salicylic acid-induced protein kinase, an important mitogen-activated protein kinase involved in herbivore resistance. These differences in salicylic acid-induced protein kinase activity were associated with substantially different levels of OS-elicited jasmonic acid, jasmonic acid-isoleucine conjugate, and ethylene bursts. Gene expression level polymorphism (ELP) determines phenotypic variation among populations, and we found the two accessions to have significantly different ELPs in the genes involved in early signaling responses to herbivory. In addition, we found differences between the Utah and the Arizona accessions in the concentrations of several secondary metabolites that contribute to N. attenuata's direct and indirect defenses. This study demonstrates significant natural variation in regulatory elements that mediate plant responses to herbivore attack, highlighting the role of ELP in producing a diversity of plant defense phenotypes.

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Section: Mapk Genes Have Different Transcript Levels In Ut and Az Plantsmentioning

confidence: 99%

A Comparison of Two Nicotiana attenuata Accessions Reveals Large Differences in Signaling Induced by Oral Secretions of the Specialist Herbivore Manduca sexta

Hettenhausen

Schuman

et al. 2008

Plant Physiology

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“…Current understanding indicates that in plants, as in yeast, separate pathways are involved in osmotic adjustment and ion homeostasis (65,66). Indeed, a putative twocomponent osmosensor that may be orthologous to Sln1p has been identified in Arabidopsis, together with entities that may comprise a MAP kinase cascade responsible for osmotic signaling (67)(68)(69). The Ca 2ϩ -dependent SOS (salt oversensitive) pathway of Arabidopsis may be the functional equivalent of the yeast calcineurin pathway, at least for ion homeostasis that is necessary to mediate salt tolerance (65,66).…”

Section: Figmentioning

confidence: 99%

An Osmotically Induced Cytosolic Ca2+ Transient Activates Calcineurin Signaling to Mediate Ion Homeostasis and Salt Tolerance of Saccharomyces cerevisiae

Matsumoto

Ellsmore

Cessna

et al. 2002

Journal of Biological Chemistry

135

119

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“…A current challenge in this research area is to determine which signaling pathways in the plant make use of which MAPK components. Recent reviews have summarized our current understanding of the roles of plant MAPK pathways in cell division, development, and stress responses (Tena et al, 2001;Jonak et al, 2002;Nakagami et al, 2005).…”

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confidence: 99%

MEKK1 Is Required for flg22-Induced MPK4 Activation in Arabidopsis Plants

et al. 2006

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The Arabidopsis (Arabidopsis thaliana) gene MEKK1 encodes a mitogen-activated protein kinase kinase kinase that has been implicated in the activation of the map kinases MPK3 and MPK6 in response to the flagellin elicitor peptide flg22. In this study, analysis of plants carrying T-DNA knockout alleles indicated that MEKK1 is required for flg22-induced activation of MPK4 but not MPK3 or MPK6. Experiments performed using a kinase-impaired version of MEKK1 (K361M) showed that the kinase activity of MEKK1 may not be required for flg22-induced MPK4 activation or for other macroscopic FLS2-mediated responses. MEKK1 may play a structural role in signaling, independent of its protein kinase activity. mekk1 knockout mutants display a severe dwarf phenotype, constitutive callose deposition, and constitutive expression of pathogen response genes. This dwarf phenotype was largely rescued by introduction into mekk1 knockout plants of either the MEKK1 (K361M) construct or a nahG transgene that degrades salicylic acid. When treated with pathogenic bacteria, the K361M plants were slightly more susceptible to an avirulent strain of Pseudomonas syringae and showed a delayed hypersensitive response, suggesting a role for MEKK1 kinase activity in this aspect of plant disease resistance. Our results indicate that MEKK1 acts upstream of MPK4 as a negative regulator of pathogen response pathways, a function that may not require MEKK1's full kinase activity.

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Plant mitogen-activated protein kinase signaling cascades

Cited by 450 publications

References 49 publications

A Comparison of Two Nicotiana attenuata Accessions Reveals Large Differences in Signaling Induced by Oral Secretions of the Specialist Herbivore Manduca sexta

A Comparison of Two Nicotiana attenuata Accessions Reveals Large Differences in Signaling Induced by Oral Secretions of the Specialist Herbivore Manduca sexta

An Osmotically Induced Cytosolic Ca2+ Transient Activates Calcineurin Signaling to Mediate Ion Homeostasis and Salt Tolerance of Saccharomyces cerevisiae

MEKK1 Is Required for flg22-Induced MPK4 Activation in Arabidopsis Plants

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