Plant mechanosensitive ion channels: an ocean of possibilities

Basu, Debarati; Haswell, Elizabeth S.

doi:10.1016/j.pbi.2017.07.002

Cited by 130 publications

(103 citation statements)

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“…Mechanosensitive ion channels are membrane-localized, tension-gated proteins that are activated upon membrane stretch, thus converting mechanical stimuli to ion transport (Basu & Haswell, 2017;Hamant & Haswell, 2017). Arabidopsis MID1-COMPLEMENTING ACTIVITY1 (MCA1) is a putative stretch-activated Ca 2+ channel (Nakagawa et al, 2007) (Fig.…”

Section: Reviewmentioning

confidence: 99%

“…The homolog of MCA1 has also been characterized in maize and functions to coordinate organ growth and patterning, likely by transmitting extrinsic and intrinsic cues via Ca 2+ (Rosa et al, 2017). For a full overview of mechanosensitive ion channels other than MCA1, we highly recommended that readers refer to recent review articles by Hamilton et al (2015), Basu & Haswell (2017), and Hamant & Haswell (2017). For a full overview of mechanosensitive ion channels other than MCA1, we highly recommended that readers refer to recent review articles by Hamilton et al (2015), Basu & Haswell (2017), and Hamant & Haswell (2017).…”

Section: Reviewmentioning

confidence: 99%

“…These data imply that mechanosensing is involved in CWI maintenance. For a full overview of mechanosensitive ion channels other than MCA1, we highly recommended that readers refer to recent review articles by Hamilton et al (2015), Basu & Haswell (2017), and Hamant & Haswell (2017).…”

Section: Reviewmentioning

confidence: 99%

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A wall with integrity: surveillance and maintenance of the plant cell wall under stress

2019

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Summary The structural and functional integrity of the cell wall needs to be constantly monitored and fine‐tuned to allow for growth while preventing mechanical failure. Many studies have advanced our understanding of the pathways that contribute to cell wall biosynthesis and how these pathways are regulated by external and internal cues. Recent evidence also supports a model in which certain aspects of the wall itself may act as growth‐regulating signals. Molecular components of the signaling pathways that sense and maintain cell wall integrity have begun to be revealed, including signals arising in the wall, sensors that detect changes at the cell surface, and downstream signal transduction modules. Abiotic and biotic stress conditions provide new contexts for the study of cell wall integrity, but the nature and consequences of wall disruptions due to various stressors require further investigation. A deeper understanding of cell wall signaling will provide insights into the growth regulatory mechanisms that allow plants to survive in changing environments.

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Section: Reviewmentioning

confidence: 99%

Section: Reviewmentioning

confidence: 99%

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A wall with integrity: surveillance and maintenance of the plant cell wall under stress

2019

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“…Each Ec MscS monomer contributes three transmembrane (TM) domains and a relatively large soluble cytoplasmic domain. Like other MscS‐like superfamily proteins, MSL1, MSL2, and MSL3 share a conserved region corresponding to the pore‐lining helix and about 100 amino acids of the cytoplasmic C‐terminus called the MscS domain (Basu & Haswell, , indicated in yellow in Figure ). Outside of this domain, the topology of organellar MSL channels differs from Ec MscS and from each other in a number of ways.…”

Section: Resultsmentioning

confidence: 99%

Genetic and physical interactions between the organellar mechanosensitive ion channel homologs MSL1, MSL2, and MSL3 reveal a role for inter‐organellar communication in plant development

et al. 2019

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Plant development requires communication on many levels, including between cells and between organelles within a cell. For example, mitochondria and plastids have been proposed to be sensors of environmental stress and to coordinate their responses. Here we present evidence for communication between mitochondria and chloroplasts during leaf and root development, based on genetic and physical interactions between three M echanosensitive channel of S mall conductance‐ L ike ( MSL ) proteins from Arabidopsis thaliana . MSL proteins are Arabidopsis homologs of the bacterial M echano s ensitive c hannel of S mall conductance (MscS), which relieves cellular osmotic pressure to protect against lysis during hypoosmotic shock. MSL 1 localizes to the inner mitochondrial membrane, while MSL 2 and MSL 3 localize to the inner plastid membrane and are required to maintain plastid osmotic homeostasis during normal growth and development. In this study, we characterized the phenotypic effect of a genetic lesion in MSL 1 , both in wild type and in msl2 msl3 mutant backgrounds. msl1 single mutants appear wild type for all phenotypes examined. The characteristic leaf rumpling in msl2 msl3 double mutants was exacerbated in the msl1 msl2 msl3 triple mutant. However, the introduction of the msl1 lesion into the msl2 msl3 mutant background suppressed other msl2 msl3 mutant phenotypes, including ectopic callus formation, accumulation of superoxide and hydrogen peroxide in the shoot apical meristem, decreased root length, and reduced number of lateral roots. All these phenotypes could be recovered by molecular complementation with a transgene containing a wild type version of MSL 1 . In yeast‐based interaction studies, MSL 1 interacted with itself, but not with MSL 2 or MSL 3. These results establish that the abnormalities observed in msl2 msl3 double mutants is partially dependent on the presence of functional MSL 1 and suggest a possible role for communication between plastid and mitochondria in seedling development.

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“…Each Ec MscS monomer contributes three transmembrane (TM) domains and a relatively large soluble cytoplasmic domain. Like other MscS-like superfamily proteins, MSL1, MSL2 and MSL3 share a conserved region corresponding to the pore-lining helix and about 100 amino acids of the cytoplasmic C-terminus called the MscS domain ((Basu and Haswell, 2017), indicated in yellow in Figure 1 ). Outside of this domain, the topology of organellar MSL channels differ from Ec MscS and from each other in a number of ways.…”

Section: Resultsmentioning

confidence: 99%

Genetic and physical interactions between the organellar mechanosensitive ion channel homologs MSL1, MSL2, and MSL3 reveal a role for inter-organellar communication in plant development

Lee

Wilson

Richardson

et al. 2018

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8 USA 9 10 keywords: mechanosensitive channel, Arabidopsis, mitochondria, chloroplast, reactive oxygen 11 species 12 13 2 ABSTRACT 14 15 Plant development requires communication on many levels, including between cells and between 16 organelles within a cell. For example, mitochondria and plastids have been proposed to be sensors 17 of environmental stress and to coordinate their responses. Here we present evidence for 18 communication between mitochondria and chloroplasts during leaf and root development, based 19 on genetic and physical interactions between three Mechanosensitive channels of Small 20 conductance-Like (MSL) proteins from Arabidopsis thaliana. MSL proteins are Arabidopsis 21 homologs of the bacterial Mechanosensitive channel of Small conductance (MscS), which relieves 22 cellular osmotic pressure to protect against lysis during hypoosmotic shock. MSL1 localizes to the 23 inner mitochondrial membrane, while MSL2 and MSL3 localize to the inner plastid membrane 24and are required to maintain plastid osmotic homeostasis during normal growth and development. 25In this study, we characterized the phenotypic effect of a genetic lesion in MSL1, both in wild type 26 and in msl2 msl3 mutant backgrounds. msl1 single mutants appear wild type for all phenotypes 27 examined. The characteristic leaf rumpling in msl2 msl3 double mutants was exacerbated in the 28 msl1 msl2 msl3 triple mutant. However, the introduction of the msl1 lesion into the msl2 msl3 29 mutant background suppressed other msl2 msl3 mutant phenotypes, including ectopic callus 30 formation, accumulation of superoxide and hydrogen peroxide in the shoot apical meristem, 31 decreased root length, and reduced number of lateral roots. All these phenotypes could be 32 recovered by molecular complementation with a transgene containing a wild type version of MSL1. 33In yeast-based interaction studies, MSL1 interacted with itself, but not with MSL2 or MSL3. These 34 results establish that the abnormalities observed in msl2 msl3 double mutants is partially dependent 35 on the presence of functional MSL1 and suggest a possible role for communication between plastid 36 and mitochondria in seedling development.37 38 39 40 Plastids and mitochondria are found in almost every plant cell and are involved in all aspects of 41 plant biology. In plants, as in animals, mitochondria are involved in multiple cellular processes, 42 including cellular respiration and co-enzyme synthesis (Schertl and Braun, 2014; Rébeillé et al., 43 2007). Plastids are responsible for photosynthesis and a range of other biosynthetic reactions-44 including the production of starch, some amino acids, fatty acids and lipids, pigments, hormones 45 and volatiles (Neuhaus:2000eh; Rolland et al., 2018). Some plastids play a unique role in plant 46 biology: amyloplasts in the root tip and the shoot endodermis are essential for gravity response 47 (Toyota:2013fe; Su et al., 2017). A recent report argues that plastids of the leaf epidermis can serve 48 as stress sensors (Beltrán et al., 2018). Whi...

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Plant mechanosensitive ion channels: an ocean of possibilities

Cited by 130 publications

References 60 publications

A wall with integrity: surveillance and maintenance of the plant cell wall under stress

A wall with integrity: surveillance and maintenance of the plant cell wall under stress

Genetic and physical interactions between the organellar mechanosensitive ion channel homologs MSL1, MSL2, and MSL3 reveal a role for inter‐organellar communication in plant development

Genetic and physical interactions between the organellar mechanosensitive ion channel homologs MSL1, MSL2, and MSL3 reveal a role for inter-organellar communication in plant development

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