Plant immune receptor pathways as a united front against pathogens

Yuan, Minhang; Cai, Boying; Xin, Xiu-Fang

doi:10.1371/journal.ppat.1011106

Cited by 4 publications

(1 citation statement)

References 43 publications

(62 reference statements)

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“…NLRs function as “sensors” that recognize effectors, or as “helpers” that mediate signaling downstream of sensor NLRs (Jubic et al ., 2019). Recent studies demonstrated that PTI and ETI work together to mutually potentiate the immune response (Yuan et al ., 2021b; Yuan et al ., 2023). NLR-mediated signaling is dependent on multiple PTI-associated components such as BAK1, SOBIR1, or BIK1 in a PTI-independent manner, while TNL genes that are up-regulated during early PTI boost immune responses (Ngou et al ., 2021; Tian et al ., 2021; Yuan et al ., 2021a).…”

Section: Introductionmentioning

confidence: 99%

The receptor-like kinase BIR1 inhibits elicitor-induced plasmodesmata callose deposition and PTI gene expression and requires EDS1 and SOBIR1 to cause dose-dependent cell-death in Arabidopsis

Guzmán-Benito

Robinson

Hua

et al. 2023

Preprint

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The receptor-like kinase BIR1 functions as a negative regulator of cell death and defense in Arabidopsis. Previous studies showed that BIR1 expression is up-regulated during infections with microbes and viruses. However, the biological consequences of BIR1 induction remain unknown. Here, we use a DEX-inducible expression system in Arabidopsis to investigate the outputs associated with physiological and non-physiological levels of BIR1 expression. We show that BIR1 induction at physiological levels significantly interferes with gene expression and plasmodesmata callose deposition triggered by canonical PTI elicitors. We found that plants that accumulated non-physiological doses of BIR1 displayed morphological defects that concur with transcriptomic changes in multiple plant defense genes. We provide experimental evidence that EDS1 and SOBIR1 are required for the ETI-type cell death phenotypes associated to non-physiological levels of BIR1. Here we propose that BIR1 induction may represent a pathogen-triggered mechanism to modulate plant defenses during infection. Our model posits that when BIR1 regulation is lost, BIR1 integrity is sensed by one or several guarding resistance (R) proteins to initiate an ETI-like response, in which SOBIR1 cooperates with EDS1 to transduce signals downstream of R proteins.

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Section: Introductionmentioning

confidence: 99%

The receptor-like kinase BIR1 inhibits elicitor-induced plasmodesmata callose deposition and PTI gene expression and requires EDS1 and SOBIR1 to cause dose-dependent cell-death in Arabidopsis

Guzmán-Benito

Robinson

Hua

et al. 2023

Preprint

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MAPK Cascades in Plant Microbiota Structure and Functioning

Van Gerrewey,

Chung

2024

J Microbiol.

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Plant disease resistance outputs regulated by AP2/ERF transcription factor family

Ma,

Sun,

et al. 2024

Stress Biology

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Plants have evolved a complex and elaborate signaling network to respond appropriately to the pathogen invasion by regulating expression of defensive genes through certain transcription factors. The APETALA2/ethylene response factor (AP2/ERF) family members have been determined as key regulators in growth, development, and stress responses in plants. Moreover, a growing body of evidence has demonstrated the critical roles of AP2/ERFs in plant disease resistance. In this review, we describe recent advances for the function of AP2/ERFs in defense responses against microbial pathogens. We summarize that AP2/ERFs are involved in plant disease resistance by acting downstream of mitogen activated protein kinase (MAPK) cascades, and regulating expression of genes associated with hormonal signaling pathways, biosynthesis of secondary metabolites, and formation of physical barriers in an MAPK-dependent or -independent manner. The present review provides a multidimensional perspective on the functions of AP2/ERFs in plant disease resistance, which will facilitate the understanding and future investigation on the roles of AP2/ERFs in plant immunity.

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Plant immune receptor pathways as a united front against pathogens

Cited by 4 publications

References 43 publications

The receptor-like kinase BIR1 inhibits elicitor-induced plasmodesmata callose deposition and PTI gene expression and requires EDS1 and SOBIR1 to cause dose-dependent cell-death in Arabidopsis

The receptor-like kinase BIR1 inhibits elicitor-induced plasmodesmata callose deposition and PTI gene expression and requires EDS1 and SOBIR1 to cause dose-dependent cell-death in Arabidopsis

MAPK Cascades in Plant Microbiota Structure and Functioning

Plant disease resistance outputs regulated by AP2/ERF transcription factor family

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