Plant Extracts to Alleviating Heat Stress in Dairy Cows

Guo, Yongmei; Li, Li; Yan, Sumei; Shi, Binlin

doi:10.3390/ani13182831

Cited by 1 publication

(1 citation statement)

References 89 publications

(99 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This includes reduced MDA concentration in seminal plasma, increased total antioxidant capacity (TAC) concentration in seminal plasma, elevated total functional sperm counts, higher percentages of integrated sperm membranes, improved sperm motility, and enhanced viability [ 30 ]. Recent studies have highlighted several natural and synthetic antioxidants, including sulforaphane, periplaneta americana peptide, resveratrol, astaxanthin, growth hormones, melatonin, and celastrol, that can effectively prevent the apoptosis of granulosa cells and enhance their antioxidant activity, ensuring their normal functionality [ 153 , 154 ]. An overview of the impact of various antioxidant supplementation strategies on safeguarding mammalian reproductive cells from the adverse effects of heat-stress-induced oxidative stress and apoptosis is summarized in Table 2 .…”

Section: Role Of Exogenous Antioxidant Supplementation In Relieving H...mentioning

confidence: 99%

Advancements in Genetic Biomarkers and Exogenous Antioxidant Supplementation for Safeguarding Mammalian Cells against Heat-Induced Oxidative Stress and Apoptosis

Khan,

Chen

et al. 2024

Antioxidants

View full text Add to dashboard Cite

Heat stress represents a pervasive global concern with far-reaching implications for the reproductive efficiency of both animal and human populations. An extensive body of published research on heat stress effects utilizes controlled experimental environments to expose cells and tissues to heat stress and its disruptive influence on the physiological aspects of reproductive phenotypic traits, encompassing parameters such as sperm quality, sperm motility, viability, and overall competence. Beyond these immediate effects, heat stress has been linked to embryo losses, compromised oocyte development, and even infertility across diverse species. One of the primary mechanisms underlying these adverse reproductive outcomes is the elevation of reactive oxygen species (ROS) levels precipitating oxidative stress and apoptosis within mammalian reproductive cells. Oxidative stress and apoptosis are recognized as pivotal biological factors through which heat stress exerts its disruptive impact on both male and female reproductive cells. In a concerted effort to mitigate the detrimental consequences of heat stress, supplementation with antioxidants, both in natural and synthetic forms, has been explored as a potential intervention strategy. Furthermore, reproductive cells possess inherent self-protective mechanisms that come into play during episodes of heat stress, aiding in their survival. This comprehensive review delves into the multifaceted effects of heat stress on reproductive phenotypic traits and elucidates the intricate molecular mechanisms underpinning oxidative stress and apoptosis in reproductive cells, which compromise their normal function. Additionally, we provide a succinct overview of potential antioxidant interventions and highlight the genetic biomarkers within reproductive cells that possess self-protective capabilities, collectively offering promising avenues for ameliorating the negative impact of heat stress by restraining apoptosis and oxidative stress.

show abstract

Section: Role Of Exogenous Antioxidant Supplementation In Relieving H...mentioning

confidence: 99%