Plant E3 Ligases and Their Role in Abiotic Stress Response

Al-Saharin, Raed; Hellmann, Hanjo; Mooney, Sutton

doi:10.3390/cells11050890

Cited by 51 publications

(31 citation statements)

References 220 publications

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“…Stress Associated Protein5 (SAP5) is another E3 that functions upstream of DRIP1/2 ligases and promotes their degradation, thereby modulating drought-stress responses positively in Arabidopsis and wheat. Moreover, Arabidopsis SAP5 has been reported as a positive regulator of salt and osmotic stress tolerance (Al-Saharin et al, 2022; Table 3). Plant U-box type E3s are also known to participate in the regulation of drought stress tolerance.…”

Section: E Ligase Function During Drought Stressmentioning

confidence: 99%

“…Similarly, overexpression of AtPUB48, a U-box type E3, acts as a positive regulator of heat stress-responsive genes and increases their expression. Following the fundamental theme of imparting stress tolerance by promoting turnover of negative elements and stabilization of positive elements, rice RING E3 ligase, HEAT-INDUCED RING FINGER PROTEIN1 (OsHIRP1), show heat stress Frontiers in Plant Science frontiersin.org tolerance through proteasomal degradation of ALDO/KETO REDUCTASE4 (OsARK4) and HIRP1-REGULATED KINASE1 (OsHRK1) that likely affects heat-stress tolerance negatively (Al-Saharin et al, 2022).…”

Section: Ubiquitination and Temperature Stress Responsementioning

confidence: 99%

“…A well-described example of RING-type E3s is Dehydration Responsive Binding Element 2A (DREB2A) Interacting Protein1 (DRIP1) and DRIP2, which are involved in the regulation of stress-responsive ERF/AP2 transcription factor DREB2A that functions upstream of many drought- and salt-stress inducible genes ( Figure 4A ) (Qin et al, 2008 ). Accumulation of DREB2A only under drought conditions, in vitro ubiquitination of DREB2A by DRIP1, and increased stabilization of DREB2A in drip1/drip2 double mutants indicate that the abundance of DREB2A is negatively regulated by DRIP1/2 (Sakuma et al, 2006a , b ; Qin et al, 2008 ; Al-Saharin et al, 2022 ). Moreover, the increased abundance of DREB2A upon UPS inhibition and enhanced drought tolerance in drip1/drip2 double mutants was concomitant with a significant increase in expression of several drought-inducible genes specifically regulated by DREB2A (Qin et al, 2008 ).…”

Section: Ubiquitinationmentioning

confidence: 99%

“…Other members of the U-box family that are known to downregulate drought tolerance are PUB19, PUB22, and PUB23 ( Table 3 ). On contrary, PUB46 and PUB48 are reported as positive regulators of drought stress since their mutations lead to drought hypersensitivity, though their potential targets remain elusive (Al-Saharin et al, 2022 ). Rice PUB41 (OsPUB41) is known to have a negative influence on drought-responsive signaling as it mediates the degradation of Chloride Channel6 (OsCLC6), which is critical for modulating chloride homeostasis under water deficit conditions.…”

Section: Ubiquitinationmentioning

confidence: 99%

“…Conversely, PUB26 affects salt stress response negatively ( Table 3 ) by interacting with one of the ATPase subunits of 26S proteasome, T. aestivum Regulatory Particle Triple-ATPase2A (TaRPT2a). Its gene expression is salt inducible, but the molecular mechanism underlying this interaction requires further studies (Al-Saharin et al, 2022 ). SALT TOLERANCE RING FINGER 1 (STRF1) is a membrane-associated RING-H2 type E3 ligase annotated as a positive modulator of salt stress in Arabidopsis ( Table 3 ).…”

Section: Ubiquitinationmentioning

confidence: 99%

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Current perspectives of ubiquitination and SUMOylation in abiotic stress tolerance in plants

Singh

Yadav

et al. 2022

Front. Plant Sci.

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Post-translational modification (PTM) is a critical and rapid mechanism to regulate all the major cellular processes through the modification of diverse protein substrates. Substrate-specific covalent attachment of ubiquitin and Small Ubiquitin-Like Modifier (SUMO) with the target proteins, known as ubiquitination and SUMOylation, respectively, are crucial PTMs that regulate almost every process in the cell by modulating the stability and fidelity of the proteins. Ubiquitination and SUMOylation play a very significant role to provide tolerance to the plants in adverse environmental conditions by activating/deactivating the pre-existing proteins to a great extent. We reviewed the importance of ubiquitination and SUMOylation in plants, implicating its prospects in various abiotic stress regulations. An exhaustive study of molecular mechanisms of ubiquitination and SUMOylation of plant proteins and their role will contribute to the understanding of physiology underlying mitigation of the abiotic stresses and survival in plants. It will be helpful to strategize the improvement of crops for abiotic stress tolerance.

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Section: E Ligase Function During Drought Stressmentioning

confidence: 99%

Section: Ubiquitination and Temperature Stress Responsementioning

confidence: 99%

Section: Ubiquitinationmentioning

confidence: 99%

Section: Ubiquitinationmentioning

confidence: 99%

Section: Ubiquitinationmentioning

confidence: 99%

See 3 more Smart Citations

Current perspectives of ubiquitination and SUMOylation in abiotic stress tolerance in plants

Singh

Yadav

et al. 2022

Front. Plant Sci.

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Genetic variability and QTL mapping of morphological traits and inflorescence prolificacy in African bermudagrass

Yu,

Fontanier,

Yan

et al. 2024

Crop Science

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African bermudagrass (Cynodon transvaalensis Burtt‐Davy) (2n = 2x = 18) has unique morphological characteristics such as finer leaf blades and shorter internodes that are important to improving turf qualities (i.e., texture and density) as compared to other Cynodon species. It has been extensively used to cross with common bermudagrass (Cynodon dactylon Pers. var. dactylon) in developing high‐quality interspecific [C. dactylon (L.) Pers. × C. transvaalensis Burtt‐Davy] F1 hybrid cultivars for turf use. However, the molecular basis of its morphological variation is unknown. Accordingly, the objectives of this study were to estimate the heritability and identify quantitative trait loci (QTL) associated with morphological and reproductive traits. A first‐generation self‐pollinated (S1) population of 109 individuals was evaluated for plant height (PH), leaf blade width (LBW) and leaf blade length, stem internode diameter and length, and inflorescence prolificacy (IP) in a replicated field trial over three seasons (2018–2020). The broad‐sense heritability estimates ranged from 0.31 (PH) to 0.80 (IP). Twenty‐four QTL were identified and nine of them were consistent ones. Fifteen candidate genes were found at a major and consistent QTL region associated with LBW. Frequent QTL colocations were found among morphological traits and between morphological traits and IP, partially explaining the significant correlation. The findings provide critical information and resources toward understanding the genetic basis associated with morphological and reproductive traits within C. transvaalensis and could contribute to marker‐assisted selection for breeding new turf‐type bermudagrass cultivars.

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Genomic‐wide analysis reveals seven in absentia genes regulating grain development in wheat (Triticum aestivum L.)

Chen,

Miao,

Jing

et al. 2024

The Plant Genome

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Seven in absentia proteins, which contain a conserved SINA domain, are involved in regulating various aspects of wheat (Triticum aestivum L.) growth and development, especially in response to environmental stresses. However, it is unclear whether TaSINA family members are involved in regulating grain development until now. In this study, the expression pattern, genomic polymorphism, and relationship with grain‐related traits were analyzed for all TaSINA members. Most of the TaSINA genes identified showed higher expression levels in young wheat spikes or grains than other organs. The genomic polymorphism analysis revealed that at least 62 TaSINA genes had different haplotypes, where the haplotypes of five genes were significantly correlated with grain‐related traits. Kompetitive allele‐specific PCR markers were developed to confirm the single nucleotide polymorphisms in TaSINA101 and TaSINA109 among the five selected genes in a set of 292 wheat accessions. The TaSINA101‐Hap II and TaSINA109‐Hap II haplotypes had higher grain weight and width compared to TaSINA101‐Hap I and TaSINA109‐Hap I in at least three environments, respectively. The qRT‐PCR assays revealed that TaSINA101 was highly expressed in the palea shell, seed coat, and embryo in young wheat grains. The TaSINA101 protein was unevenly distributed in the nucleus when transiently expressed in the protoplast of wheat. Three homozygous TaSINA101 transgenic lines in rice (Oryza sativa L.) showed higher grain weight and size compared to the wild type. These findings provide valuable insight into the biological function and elite haplotype of TaSINA family genes in wheat grain development at a genomic‐wide level.

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Plant E3 Ligases and Their Role in Abiotic Stress Response

Cited by 51 publications

References 220 publications

Current perspectives of ubiquitination and SUMOylation in abiotic stress tolerance in plants

Current perspectives of ubiquitination and SUMOylation in abiotic stress tolerance in plants

Genetic variability and QTL mapping of morphological traits and inflorescence prolificacy in African bermudagrass

Genomic‐wide analysis reveals seven in absentia genes regulating grain development in wheat (Triticum aestivum L.)

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