Plant cell culture extract of <i>Cirsium eriophorum</i> with skin pore refiner activity by modulating sebum production and inflammatory response

Laneri, Sonia; Dini, Irene; Tito, Annalisa; Lorenzo, Ritamaria Di; Bimonte, Marida; Tortora, Assunta; Zappelli, Claudia; Angelillo, Maura; Bernardi, Antonietta; Sacchi, Antonia; Colucci, Maria Gabriella; Apone, Fabio

doi:10.1002/ptr.6832

Cited by 16 publications

(10 citation statements)

References 34 publications

(42 reference statements)

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“…5). It is thought that the problems with pores are caused by an increase in sebum amount, an increase in hole volume due to clogging of keratin plugs, and a decrease in elasticity around the pores (Laneri et al , 2021). In our study, it appears that the improvement in pore issues was not caused by repairing the skin structure and improving elasticity around pores by collagen production (Schütz et al ., 2019), but by promoting turnover by improving TEWL.…”

Section: Improvement Of Pore Issuesmentioning

confidence: 48%

Skin improvement effects of phytosterol ester derived from rice bran

Kobayashi¹,

Nakagawa²,

Nakamura³

et al. 2022

Preprint

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Rice bran contains an abundance of phytosterols. We have developed “Riceterol EsterTM” (RSE), which consists of a phytosterol ester and fatty acids made from the by-product of extracting oil from rice bran. RSE has been registered as a cosmetic ingredient in rice bran-derived products, and its physical functions, such as its high water retention and emollient effects, are evident, although its biological functions remain poorly understood. In this study, we clarified the biological effectiveness of RSE. Treatment of 0.01% RSE to normal human fibroblasts cell (Hs68) resulted in increased amounts of hyaluronic acid and type III collagen. On the other hand, in the face application test with human volunteers, a significantly reduced amount of trans-epidermal water loss (TEWL) was found in the 8th and 12th weeks. By image analysis, improvements in facial redness and pore troubles were also observed using a visual analog scale (VAS) questionnaire. It is suggested that RSE improves barrier function and maintains the repair of the dermis structure.

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Section: Improvement Of Pore Issuesmentioning

confidence: 48%

Skin improvement effects of phytosterol ester derived from rice bran

Kobayashi¹,

Nakagawa²,

Nakamura³

et al. 2022

Preprint

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“…Zinc has been reported to reduce sebum production in vivo and to inhibit SRD5A via non-competitive inhibition of testosterone binding to SRD5A and the decreasing formation of the NADPH cofactor [ 13 ]. Many herbal extracts could alleviate androgen-stimulated sebum production from potent SRD5A inhibitor activity [ 44 , 52 , 53 ]. Moreover, saw palmetto, sesame seeds, and argan oil, which have high contents of polyphenolic compounds, have been introduced for use in facial sebum control [ 1 ].…”

Section: Resultsmentioning

confidence: 99%

“…In the previous study, excessive sebum levels, age, and the male gender affected facial pore size enlargement [ 56 ]. Facial pore sizes further play an important role in releasing sebum from sebaceous glands [ 52 ]. Androgen is predominantly exerted to the proliferation of sebocytes and sebum production [ 56 , 57 ].…”

Section: Resultsmentioning

confidence: 99%

In Vitro and In Vivo Regulation of SRD5A mRNA Expression of Supercritical Carbon Dioxide Extract from Asparagus racemosus Willd. Root as Anti-Sebum and Pore-Minimizing Active Ingredients

et al. 2022

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Oily skin from overactive sebaceous glands affects self-confidence and personality. There is report of an association between steroid 5-alpha reductase gene (SRD5A) expression and facial sebum production. There is no study of the effect of Asparagus racemosus Willd. root extract on the regulation of SRD5A mRNA expression and anti-sebum efficacy. This study extracted A. racemosus using the supercritical carbon dioxide fluid technique with ethanol and investigated its biological compounds and activities. The A. racemosus root extract had a high content of polyphenolic compounds, including quercetin, naringenin, and p-coumaric acid, and DPPH scavenging activity comparable to that of the standard L-ascorbic acid. A. racemosus root extract showed not only a significant reduction in SRD5A1 and SRD5A2 mRNA expression by about 45.45% and 90.86%, respectively, but also a reduction in the in vivo anti-sebum efficacy in male volunteers, with significantly superior percentage changes in facial sebum production and a reduction in the percentages of pore area after 15 and 30 days of treatment. It can be concluded that A. racemosus root extract with a high content of polyphenol compounds, great antioxidant effects, promising downregulation of SRD5A1 and SRD5A2, and predominant facial sebum reduction and pore-minimizing efficacy could be a candidate for an anti-sebum and pore-minimizing active ingredient to serve in functional cosmetic applications.

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“…[ 8 ], whose profile and level depending on the pedoclimatic condition and agriculture practice [ 9 , 10 ]. Bioactive extracts are also obtained by algae, mushrooms, by-products of plant origins [ 11 , 12 , 13 , 14 ], and plant cell culture technology [ 15 , 16 ]. The latter is a natural and suitable technology used to make hair care, makeup, skincare, and supplement ingredients.…”

Section: Plant Cell Culture Technologymentioning

confidence: 99%

The New Challenge of Green Cosmetics: Natural Food Ingredients for Cosmetic Formulations

Dini

Laneri

2021

Molecules

Self Cite

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Nowadays, much attention is paid to issues such as ecology and sustainability. Many consumers choose "green cosmetics", which are environmentally friendly creams, makeup, and beauty products, hoping that they are not harmful to health and reduce pollution. Moreover, the repeated mini-lock downs during the COVID-19 pandemic have fueled the awareness that body beauty is linked to well-being, both external and internal. As a result, consumer preferences for makeup have declined, while those for skincare products have increased. Nutricosmetics, which combines the benefits derived from food supplementation with the advantages of cosmetic treatments to improve the beauty of our body, respond to the new market demands. Food chemistry and cosmetic chemistry come together to promote both inside and outside well-being. A nutricosmetic optimizes the intake of nutritional microelements to meet the needs of the skin and skin appendages, improving their conditions and delaying aging, thus helping to protect the skin from the aging action of environmental factors. Numerous studies in the literature show a significant correlation between the adequate intake of these supplements, improved skin quality (both aesthetic and histological), and the acceleration of wound-healing. This review revised the main foods and bioactive molecules used in nutricosmetic formulations, their cosmetic effects, and the analytical techniques that allow the dosage of the active ingredients in the food.

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Plant cell culture extract of Cirsium eriophorum with skin pore refiner activity by modulating sebum production and inflammatory response

Cited by 16 publications

References 34 publications

Skin improvement effects of phytosterol ester derived from rice bran

Skin improvement effects of phytosterol ester derived from rice bran

In Vitro and In Vivo Regulation of SRD5A mRNA Expression of Supercritical Carbon Dioxide Extract from Asparagus racemosus Willd. Root as Anti-Sebum and Pore-Minimizing Active Ingredients

The New Challenge of Green Cosmetics: Natural Food Ingredients for Cosmetic Formulations

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