Plant‐based active photoprotectants for sunscreens

Abstract

Excessive exposure to the sun's radiation is the major exogenous mediator of skin damage, which accelerates skin ageing and increases the risk of developing skin cancer. Compounds with photoprotectant activity are extremely useful for decreasing the effect of ultraviolet (UV) radiation on the skin; however, numerous sun filters, especially organic sunscreens, are allergenic. Therefore, the development of formulations containing plant extracts, which may be potentially safer, is extensively being explored. Plant-based cosmetics are commonly used to avoid skin ageing because they contain antioxidant agents that minimize free radical activity, and numerous studies have investigated the skin-protectant effects of related plant species. In addition to their antioxidant properties, plant-based cosmetics protect the skin against solar radiation because they contain polyphenols such as flavonoids and carotenoids. Therefore, this study aims to present a review of plant species commonly used in sunscreens to protect the skin against damage due to sunlight exposure.R esum e L'exposition excessive au rayonnement du soleil est le principal m ediateur exog ene de dommages a la peau, ce qui acc el ere le vieillissement de la peau et augmente le risque de d evelopper un cancer de la peau. Les compos es ayant une activit e photo-protectrice sont extrêmement utiles pour r eduire l'effet du rayonnement ultraviolet (UV) sur la peau; Toutefois, de nombreux filtres solaires, en particulier les filtres solaires organiques, sont allergisantes. Par cons equent, le d eveloppement de formulations contenant des extraits de plantes, qui peuventêtre potentiellement plus sûres, est largement explor ee. Des cosm etiques a base de plantes sont couramment utilis es pour eviter le vieillissement de la peau, car ils contiennent des agents antioxydants qui r eduisent l'activit e des radicaux libres, et de nombreuses etudes ont etudi e les effets protecteurs des esp eces de plantes apparent ees. En plus de leurs propri et es antioxydantes, les cosm etiques a base de plantes prot egent la peau contre le rayonnement solaire, car ils contiennent des polyph enols tels que les flavono€ ıdes et les carot eno€ ıdes. Par cons equent, cette etude vise a pr esenter un examen des esp eces v eg etales couramment utilis ees dans les ecrans solaires pour prot eger la peau contre les dommages dus a l'exposition au soleil.

In-vitro and in-vivo Sunscreen Activity of Active Compounds Isolated from Fruits of Phaleria marcocarpha (Scheff.) Boerl

“…Natural sunscreens generally contain antioxidants such as polyphenols, flavonoids and carotenoids that can minimize the effects of free radicals contained in UV light. 15,21 The effectiveness of sunscreen can be measured by in-vitro and in-vivo assay. In-vitro assays are performed indirectly with samples while in-vivo are performed directly on the skin of animals or humans.…”

Strawberry-Based Cosmetic Formulations Protect Human Dermal Fibroblasts against UVA-Induced Damage

“…Even if ultraviolet (UV) radiation possesses some health benefits, such as the stimulation of cholecalciferol production, and is often used to cure some skin pathologies, such as vitiligo and psoriasis, it remains the principal cause of different skin disorders [1,2]. The main pathological effects of UV radiation range from erythema and premature aging to cancer; at the same time, it is able to induce cellular modifications such as alterations in elastic fibers and collagen, loss of subcutaneous adipose tissue, and photo-carcinogenic changes [1].…”

“…The main pathological effects of UV radiation range from erythema and premature aging to cancer; at the same time, it is able to induce cellular modifications such as alterations in elastic fibers and collagen, loss of subcutaneous adipose tissue, and photo-carcinogenic changes [1]. UVA makes up 95% of incident light and is more penetrating than UVB, reaching the subcutaneous tissue, and affecting both dermal and epidermal skin structures [3].…”

“…Sunscreens protect the skin against cancer and they also prevent the onset of other skin diseases caused by solar radiation, such as wrinkle formation, collagen loss, undesired pigmentation, and aging. Indeed, the topical application of sunscreens represents an effective precautionary measure against these problems mainly in regions with high solar radiation levels [1]. Recently, compounds derived from natural sources have attracted remarkable attention for their implementation in sunscreen products and have encouraged the market trend towards natural cosmetics.…”

Development of sunscreen products containing passion fruit seed extract

“…Application of sunscreen protects skin from damages; therefore, it is accounted as an important strategy to combat adverse effect of sun exposure. Currently, plant-based actives are receiving increased attention (Cefali et al, 2016;Silva et al, 2016). Those of fruit residues as high value-added chemical from food supply chain wastes are established and emerging globally.…”