Plant‐Associated Microorganisms (Endophytes) as a New Source of Bioactive Natural Products

Strobel, Gary A.

doi:10.1002/9783527619771.ch4

Cited by 5 publications

(5 citation statements)

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“…Almost every plant taxon is colonized by a highly diverse and finely structured microbe communities [3]. Each plant compartment serves as a unique ecological niche for microbial entities, hosting a distinct microbial assembly as compared to other plant tissues, including roots, stems, leaves, flowers, and seeds [4–8].…”

Section: Introductionmentioning

confidence: 99%

Niche differentiation rather than biogeography shapes the diversity and composition of microbiome of Cycas panzhihuaensis

Zheng

Gong

2019

Microbiome

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BackgroundGiven their adaptation to nutrient-poor and drought environments, cycads are vital models for plant-microbiome interaction research because they are likely to host an important reservoir of beneficial microbes that may support cycad survival. However, a comprehensive understanding of the diversity and community composition of microbiome associated with different plant compartments as well as bulk soils of cycad species remains elusive.MethodAn extensive investigation of species diversity and community composition of bacterial and fungal microbiome in roots, seeds, unfertilized seeds, ovules, pollens, and soils of Cycas panzhihuaensis L. Zhou & S. Y. Yang has been conducted by high-through sequencing technology. Moreover, principal component analysis (PCA), hierarchical cluster analysis (HCA), and heatmap analysis were applied to test the niche-specific effect and biogeography factor among different sample types of this cycad species.ResultsHighly diverse microbiota and significant variation of community structure were found among different compartments of C. panzhihuaensis. Soils exhibited a remarkable differentiation of bacterial community composition compared to the other five plant organs as revealed by PCA, HCA, and heatmap analyses. Different compartments possessed unique core microbial taxa with Pseudomonadaceae and Nectriaceae shared among them. According to the indicator species analysis, there was almost no differentiation of dominant microbiomes with regard to the geography of the host cycad. Two main transmission models existed in the C. panzhihuaensis.ConclusionsEach sample type represented a unique niche and hosted a niche-specific core microbial taxa. Contrary to previous surveys, biogeography hardly exerted impact on microbial community variation in this study. The majority of the cycad-associated microbes were horizontally derived from soils and/or air environments with the rest vertically inherited from maternal plants via seeds. This study offers a robust knowledge of plant-microbiome interaction across various plant compartments and soils and lends guidelines to the investigation of adaptation mechanism of cycads in arid and nutrient-poor environments as well as their evolutionary conservation.

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Section: Introductionmentioning

confidence: 99%

Niche differentiation rather than biogeography shapes the diversity and composition of microbiome of Cycas panzhihuaensis

Zheng

Gong

2019

Microbiome

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“…In the past two decades, many valuable bioactive compounds with antimicrobial, insecticidal, cytotoxic and anticancer activities have been successfully discovered from endophytic fungi. These bioactive compounds could be mainly classified as alkaloids, terpenoids, steroids, quinones, isocoumarins, lignans, phenylpropanoids, phenols and lactones [ 5 , 6 , 7 , 8 , 9 ].…”

Section: Introductionmentioning

confidence: 99%

Enhancement of Diepoxin ζ Production by Yeast Extract and Its Fractions in Liquid Culture of Berkleasmium-Like Endophytic Fungus Dzf12 from Dioscorea zingiberensis

Zhao

Zheng

et al. 2011

Molecules

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This study was to examine the effects of yeast extract (YE) and its fractions (YE1 and YE2) on the growth and diepoxin ζ (a spirobisnaphthalene with a diversity of bioactivities) production in liquid culture of Berkleasmium-like endophytic fungus Dzf12 from Dioscorea zingiberensis. When YE was applied to the liquid medium at 10 g/L on day 3 of culture, the diepoxin ζ production was most effectively enhanced 3.2-fold (378.70 mg/L versus 120.09 mg/L in control) after another 10 days culture. Feeding with 15 g/L of YE on day 9, the mycelia biomass reached 16.44 g/L, about 2.3-fold in comparison with the control (7.15 g/L). The polysaccharide fraction (YE1) was mainly responsible for stimulating diepoxin ζ accumulation, and the non-polysaccharide fraction (YE2) was mainly responsible for promoting mycelia growth. The results showed that the diepoxin ζ production in liquid culture of endophyte Dzf12 could be effectively enhanced by YE and its fractions.

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“…These particular 85 characteristics lead them to be employed in several biotechnological applications. Thanks to their secondary 86 metabolites, endophytes are employed as medicinal remedies (Strobel 2007;Qin et al 2011) and as a tool for 87 phytoremediation of organic contaminants giving their ability to degrade xenobiotics (Lodewyckx et al 2002;6 Arid regions are characterized by low rainfall and substantial unvegetated areas, which offer a typical ecosystem 121 with patchwork-shaped microbial assemblages (Pointing and Belnap 2012;Nagy et al 2005). In the recent years,…”

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confidence: 99%

Plant-associated microbiomes in arid lands: diversity, ecology and biotechnological potential

et al. 2015

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Plant‐Associated Microorganisms (Endophytes) as a New Source of Bioactive Natural Products

Cited by 5 publications

References 61 publications

Niche differentiation rather than biogeography shapes the diversity and composition of microbiome of Cycas panzhihuaensis

Niche differentiation rather than biogeography shapes the diversity and composition of microbiome of Cycas panzhihuaensis

Enhancement of Diepoxin ζ Production by Yeast Extract and Its Fractions in Liquid Culture of Berkleasmium-Like Endophytic Fungus Dzf12 from Dioscorea zingiberensis

Plant-associated microbiomes in arid lands: diversity, ecology and biotechnological potential

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