Plant amine oxidases “on the move”: An update

Angelini, Riccardo; Cona, Alessandra; Federico, Rodolfo; Fincato, Paola; Tavladoraki, Paraskevi; Tisi, Alessandra

doi:10.1016/j.plaphy.2010.02.001

Cited by 173 publications

(115 citation statements)

References 46 publications

Supporting

Mentioning

112

Contrasting

Order By: Relevance

“…CuAOs oxidize Put at the primary amino group producing 4-aminobutyraldehyde (ABAL), hydrogen peroxide (H 2 O 2 ), and ammonia (Medda et al, 2009). PAOs catalyze the oxidation of Spm, Spd, and/or their acetylated derivatives at the secondary amino group (Cona et al, 2006;Angelini et al, 2010). The chemical nature of PAO reaction products depends on the enzyme source and reflects the mode of substrate oxidation.…”

mentioning

confidence: 99%

“…The chemical nature of PAO reaction products depends on the enzyme source and reflects the mode of substrate oxidation. In monocotyledons, PAOs oxidize the carbon at the endo-side of the N 4 -nitrogen of Spd and Spm, producing ABAL and N-(3-aminopropyl)-ABAL, respectively, in addition to DAP and H 2 O 2 (Cona et al, 2006;Angelini et al, 2010). In Arabidopsis, PAOs, namely AtPAO1 , AtPAO2 (Fincato et al, 2011), AtPAO3 (Moschou et al, 2008c), and AtPAO4 (Kamada-Nobusada et al, 2008), oxidize the carbon at the exo-side of the N 4 -nitrogen of Spd and Spm, giving rise to an interconversion catabolism, with the production of Spd from Spm and Put from Spd, in addition to 3-aminopropionaldehyde and H 2 O 2 .…”

mentioning

confidence: 99%

“…CuAOs and PAOs do not only contribute to important physiological processes through the regulation of cellular PA levels, but do so also through their reaction products: aminoaldehydes, DAP and, markedly, H 2 O 2 (Bouchereau et al, 1999;Walters, 2003;Cona et al, 2006;Angelini et al, 2010). In Arabidopsis, intracellular Spd-derived H 2 O 2 triggers the opening of the hyperpolarization-activated Ca 2+ -permeable channels in pollen, thus regulating pollen tube growth (Wu et al, 2010).…”

mentioning

confidence: 99%

See 2 more Smart Citations

Perturbation of Polyamine Catabolism Can Strongly Affect Root Development and Xylem Differentiation

et al. 2011

Self Cite

View full text Add to dashboard Cite

Spermidine (Spd) treatment inhibited root cell elongation, promoted deposition of phenolics in cell walls of rhizodermis, xylem elements, and vascular parenchyma, and resulted in a higher number of cells resting in G 1 and G 2 phases in the maize (Zea mays) primary root apex. Furthermore, Spd treatment induced nuclear condensation and DNA fragmentation as well as precocious differentiation and cell death in both early metaxylem and late metaxylem precursors. Treatment with either N-prenylagmatine, a selective inhibitor of polyamine oxidase (PAO) enzyme activity, or N,N 1 -dimethylthiourea, a hydrogen peroxide (H 2 O 2 ) scavenger, reverted Spd-induced autofluorescence intensification, DNA fragmentation, inhibition of root cell elongation, as well as reduction of percentage of nuclei in S phase. Transmission electron microscopy showed that N-prenylagmatine inhibited the differentiation of the secondary wall of early and late metaxylem elements, and xylem parenchymal cells. Moreover, although root growth and xylem differentiation in antisense PAO tobacco (Nicotiana tabacum) plants were unaltered, overexpression of maize PAO (SZmPAO) as well as down-regulation of the gene encoding S-adenosyl-L-methionine decarboxylase via RNAi in tobacco plants promoted vascular cell differentiation and induced programmed cell death in root cap cells. Furthermore, following Spd treatment in maize and ZmPAO overexpression in tobacco, the in vivo H 2 O 2 production was enhanced in xylem tissues. Overall, our results suggest that, after Spd supply or PAO overexpression, H 2 O 2 derived from polyamine catabolism behaves as a signal for secondary wall deposition and for induction of developmental programmed cell death.

show abstract

mentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Perturbation of Polyamine Catabolism Can Strongly Affect Root Development and Xylem Differentiation

et al. 2011

Self Cite

View full text Add to dashboard Cite

show abstract

“…Generally, the steady-state levels of Spd and Spm are more tightly regulated than those of Put through transcriptional, translational, and posttranslational control mechanisms (for recent reviews, see Handa and Mattoo, 2010;Mattoo et al, 2010). However, the intracellular pool of free polyamines depends not only on the biosynthetic rate but also on several other processes, including transport, conjugation, and degradation (Persson, 2009;Alcázar et al, 2010;Angelini et al, 2010;.…”

mentioning

confidence: 99%

Bacterial and Plant Signal Integration via D3-Type Cyclins Enhances Symptom Development in the Arabidopsis-Rhodococcus fasciansInteraction

et al. 2011

View full text Add to dashboard Cite

The phytopathogenic actinomycete Rhodococcus fascians drives its host to form a nutrient-rich niche by secreting a mixture of cytokinins that triggers plant cell division and shoot formation. The discrepancy between the relatively low amount of secreted cytokinins and the severe impact of R. fascians infection on plant development has puzzled researchers for a long time. Polyamine and transcript profiling of wild-type and cytokinin receptor mutant plants revealed that the bacterial cytokinins directly stimulated the biosynthesis of plant putrescine by activating arginine decarboxylase expression. Pharmacological experiments showed that the increased levels of putrescine contributed to the severity of the symptoms. Thus, putrescine functions as a secondary signal that impinges on the cytokinin-activated pathway, amplifying the hormone-induced changes that lead to the formation of a leafy gall. Exogenous putrescine and treatment with polyamine biosynthesis inhibitors combined with transcript and polyamine analyses of wild-type and mutant plants indicated that the direct target of both the bacterial cytokinins and plant putrescine was the expression of D3-type cyclins. Hence, the activated D-type cyclin/ retinoblastoma/E2F transcription factor pathway integrates both external and internal hormonal signals, stimulating mitotic cell divisions and inducing pathological plant organogenesis.

show abstract

“…AOs catalyze the oxidation of Put and Spd to their corresponding amino aldehydes, with the concomitant production of ammonia and H2O2 (Cona et al, 2006;Angelini et al, 2010;Planas-Portell et al, 2013). However, information regarding PA oxidation is still fragmentary because of the 10 putative AO genes that have been identified in Arabidopsis, only four have been characterized biochemically (Møller and McPherson, 1998;PlanasPortell et al, 2013).…”

Section: Polyamine Biosynthesismentioning

confidence: 99%

The Role of Polyamines in Plant Disease Resistance

Takahashi

2016

Environmental Control in Biology

View full text Add to dashboard Cite

Polyamines (PAs) are small, aliphatic amines that are found in all living cells. In plants, putrescine, spermidine, spermine, and thermospermine are known as ubiquitous PAs. They are involved in various physiological processes and environmental stress responses, including pathogen infections. Several studies have demonstrated that PAs and their catabolic products, such as H2O2 produced by diamine oxidases and polyamine oxidases, are closely involved in the activation of host defense mechanisms. This minireview briefly summarizes recent advances regarding the function of PAs during disease resistance in plants.

show abstract

Plant amine oxidases “on the move”: An update

Cited by 173 publications

References 46 publications

Perturbation of Polyamine Catabolism Can Strongly Affect Root Development and Xylem Differentiation

Perturbation of Polyamine Catabolism Can Strongly Affect Root Development and Xylem Differentiation

Bacterial and Plant Signal Integration via D3-Type Cyclins Enhances Symptom Development in the Arabidopsis-Rhodococcus fasciansInteraction

The Role of Polyamines in Plant Disease Resistance

Contact Info

Product

Resources

About